Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Arylsulfatase A
Summary
- UniProt ID
- P15289
- Gene Symbol
-
- ARSA
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P15289
- PubChem
- P15289
- SwissLipids
- The Human Metabolome Database
- HMDBP00320
- RaftProt
- P15289
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Hydrolase
- Ichthyosis
- Lipid metabolism
- Lysosome
- Metachromatic leukodystrophy
- Metal-binding
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| lipid metabolic process |
| GO Term |
|---|
| extracellular region |
| lysosome |
| extracellular exosome |
| endoplasmic reticulum lumen |
| azurophil granule lumen |
| lysosomal lumen |
| GO Term |
|---|
| calcium ion binding |
| sulfuric ester hydrolase activity |
| arylsulfatase activity |
| cerebroside-sulfatase activity |
Sequence
MGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPHA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 158 | N-linked (GlcNAc...) asparagine | |||
| 184 | N-linked (GlcNAc...) asparagine | |||
| 350 | N-linked (GlcNAc...) asparagine | |||
| 400 |
|
|||
|
|
G80966KZ
G51623PN
G82020ZR
G84155GY
G08011QI
G82348BZ
G57321FI
G64527OM
G85121LW
G72282QM
G83400DU
G05724UK
G49447IS
G08790WV
G51895WL
G10073SM
G39188ZX
G01304XG
G25637MV
G06110VR
G77852EK
G00406II
G93975QL
G66538GV
G81269JJ
G74724QE
G15407YE
G32550BI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glycosphingolipid catabolism | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| The activation of arylsulfatases | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1558 | angioedema | |
| DOID:0014667 | disease of metabolism | |
| DOID:0040085 | bacterial sepsis | |
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050441 | mucosulfatidosis | |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | |
| DOID:0050564 | autosomal dominant nonsyndromic deafness | |
| DOID:0050565 | autosomal recessive nonsyndromic deafness | |
| DOID:0050566 | X-linked nonsyndromic deafness | |
| DOID:0050569 | Seckel syndrome |
