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CD44 antigen

Summary

UniProt ID

P15379

Gene Symbol

Cd44
Ly-24

Gene ID

12505

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003403
GlyGen: P15379
PubChem: P15379
RaftProt: P15379
Re-Glyco: P15379

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Cell projection
Disulfide bond
Phosphoprotein
Proteoglycan
Receptor
Reference proteome
Secreted
Signal
Sulfation
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
extracellular region
plasma membrane
microvillus
cell projection
external side of plasma membrane
cell surface
basolateral plasma membrane
apical plasma membrane
membrane raft
lamellipodium membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
receptor-mediated endocytosis
hyaluronan catabolic process
negative regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of ERK1 and ERK2 cascade
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of CD4-positive, alpha-beta T cell proliferation
branching involved in ureteric bud morphogenesis
wound healing, spreading of cells
negative regulation of regulatory T cell differentiation
branching involved in prostate gland morphogenesis

Displaying **all 4** entries
GO Term
type II transforming growth factor beta receptor binding
hyaluronic acid binding
cargo receptor activity
channel regulator activity

Annotation information from UniProt.

Sequence

MDKFWWHTAWGLCLLQLSLAHQQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDIDASNIIDDDVSSGSTIEKSTPEGYILHTYLPTEQPTGDQDDSFFIRSTLATIASTVHSKSHAAAQKQNNWIWSWFGNSQSTTQTQEPTTSATTALMTTPETPPKRQEAQNWFSWLFQPSESKSHLHTTTKMPGTESNTNPTGWEPNEENEDETDTYPSFSGSGIDDDEDFISSTIATTPRVSARTEDNQDWTQWKPNHSNPEVLLQTTTRMADIDRISTSAHGENWTPEPQPPFNNHEYQDEEETPHATSTTPNSTAEAAATQQETWFQNGWQGKNPPTPSEDSHVTEGTTASAHNNHPSQRITTQSQEDVSWTDFFDPISHPMGQGHQTESKDTDSSHSTTLQPTAAPNTHLVEDLNRTGPLSVTTPQSHSQNFSTLHGEPEEDENYPTTSILPSSTKSSAKDARRGGSLPTDTTTSVEGYTFQYPDTMENGTLFPVTPAKTEVFGETEVTLATDSNVNVDGSLPGDRDSSKDSRGSSRTVTHGSELAGHSSANQDSGVTTTSGPMRRPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINGGNGTVEDRKPSELNGEASKSQEMVHLVNKEPSETPDQCMTADETRNLQSVDMKIGV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	GlyTouCan ID	Source
27	N-linked (GlcNAc...) asparagine		UniProt GlyGen
59	N-linked (GlcNAc...) asparagine	G20528HD	GlycoProtDB UniProt GlyGen
102	N-linked (GlcNAc...) asparagine		UniProt GlyGen
113	N-linked (GlcNAc...) asparagine		UniProt GlyGen
123	N-linked (GlcNAc...) asparagine		UniProt GlyGen
183	O-linked (Xyl...) (chondroitin sulfate) serine		UniProt GlyGen
368	N-linked (GlcNAc...) asparagine		UniProt GlyGen
425	N-linked (GlcNAc...) asparagine		UniProt GlyGen
450			GlyGen
529	N-linked (GlcNAc...) asparagine		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Cell surface interactions at the vascular wall	Mus musculus
Degradation of the extracellular matrix	Mus musculus
Hyaluronan uptake and degradation	Mus musculus
Integrin cell surface interactions	Mus musculus
Neutrophil degranulation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

International Collaboration

Acknowledgements