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Rhodopsin
Summary
- UniProt ID
- P15409
- Gene Symbol
-
- Rho
- Gene ID
- 212541
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cell projection
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Metal-binding
- Palmitate
- Phosphoprotein
- Reference proteome
- Retinal protein
- Transmembrane helix
- Vision
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| photoreceptor inner segment membrane |
| photoreceptor disc membrane |
| plasma membrane |
| cell-cell junction |
| membrane |
| Golgi apparatus |
| photoreceptor outer segment |
| photoreceptor inner segment |
| photoreceptor outer segment membrane |
| sperm midpiece |
| GO Term |
|---|
| metal ion binding |
| G protein-coupled photoreceptor activity |
| spectrin binding |
| 11-cis retinal binding |
Sequence
MNGTEGPNFYVPFSNVTGVVRSPFEQPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVVFTWIMALACAAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASATASKTETSQVAPA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of the phototransduction cascade | Mus musculus |
| G alpha (i) signalling events | Mus musculus |
| Inactivation, recovery and regulation of the phototransduction cascade | Mus musculus |
| Opsins | Mus musculus |
| The canonical retinoid cycle in rods (twilight vision) | Mus musculus |
| VxPx cargo-targeting to cilium | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110372 | retinitis pigmentosa 4 | |
| DOID:0110862 | congenital stationary night blindness autosomal dominant 1 |
