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Atrial natriuretic peptide receptor 1

Summary

UniProt ID

P16066

Gene Symbol

NPR1
ANPRA

Organism

Homo sapiens (human)

External Links

PubChem: P16066
The Human Metabolome Database: HMDBP01069

Annotation

Keyword

Chloride
Disulfide bond
GTP-binding
Glycoprotein
Lyase
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Vasoactive
cGMP biosynthesis

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

1

2

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GO Term
negative regulation of angiogenesis
negative regulation of cell growth
dopamine metabolic process
negative regulation of smooth muscle cell proliferation
blood vessel diameter maintenance
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
positive regulation of cGMP-mediated signaling
cGMP-mediated signaling
positive regulation of urine volume

Displaying **all 3** entries
GO Term
receptor complex
ANPR-A receptor complex
plasma membrane

Displaying **all 10** entries
GO Term
peptide receptor activity
protein kinase activity
G protein-coupled peptide receptor activity
hormone binding
peptide hormone binding
natriuretic peptide receptor activity
adenylate cyclase activity
guanylate cyclase activity
ATP binding
GTP binding

Annotation information from UniProt.

Sequence

MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
34	N-linked (GlcNAc...) asparagine	UniProt
45	N-linked (GlcNAc...) asparagine	UniProt
212	N-linked (GlcNAc...) asparagine	UniProt
338	N-linked (GlcNAc...) asparagine	UniProt
379	N-linked (GlcNAc...) asparagine	UniProt
386	N-linked (GlcNAc...) asparagine	UniProt
427	N-linked (GlcNAc...) asparagine	UniProt