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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
E-selectin
Summary
- UniProt ID
- P16581
- Gene Symbol
-
- SELE
- ELAM1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell adhesion
- Cell membrane
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Sushi
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of inflammatory response |
| calcium-mediated signaling |
| actin filament-based process |
| response to cytokine |
| leukocyte tethering or rolling |
| positive regulation of receptor internalization |
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| cortical cytoskeleton |
| caveola |
| membrane raft |
| clathrin-coated pit |
| external side of plasma membrane |
| perinuclear region of cytoplasm |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| metal ion binding |
| phospholipase binding |
| oligosaccharide binding |
| sialic acid binding |
Sequence
MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110755 | type 1 diabetes mellitus 18 | |
| DOID:0110756 | type 1 diabetes mellitus 19 | |
| DOID:0110757 | type 1 diabetes mellitus 20 | |
| DOID:0110758 | type 1 diabetes mellitus 21 | |
| DOID:0110759 | type 1 diabetes mellitus 22 | |
| DOID:0110760 | type 1 diabetes mellitus 23 | |
| DOID:0110761 | type 1 diabetes mellitus 24 | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111029 | hemochromatosis type 1 | |
| DOID:10127 | cerebral artery occlusion |
