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MIRAGE
Platelet glycoprotein 4
Summary
- UniProt ID
- P16671
- Gene Symbol
-
- CD36
- GP3B
- GP4
- Gene ID
- 948
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell adhesion
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Isopeptide bond
- Lipid transport
- Palmitate
- Receptor
- Reference proteome
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| specific granule membrane |
| extracellular space |
| plasma membrane |
| membrane |
| receptor complex |
| cell periphery |
| Golgi apparatus |
| external side of plasma membrane |
| cell surface |
| apical plasma membrane |
Sequence
MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLWGYRDPFLSLVPYPVTTTVGLFYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFMISYCACRSKTIK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 79 | N-linked (GlcNAc...) asparagine | |||
| 102 | N-linked (GlcNAc...) asparagine |
|
||
| 134 | N-linked (GlcNAc...) asparagine |
|
||
| 163 | N-linked (GlcNAc...) asparagine |
|
||
| 205 | N-linked (GlcNAc...) asparagine |
|
||
| 220 | N-linked (GlcNAc...) asparagine |
|
||
| 235 | N-linked (GlcNAc...) asparagine |
|
||
| 247 | N-linked (GlcNAc...) asparagine |
|
||
| 321 | N-linked (GlcNAc...) asparagine | |||
| 331 |
|
G02030ZB
G41071NU
G20312EM
G80075MS
G57776ZS
G86795LJ
G86880BF
G79666IR
G81263BG
G51413EV
G08146BT
G22310AV
G07246CJ
G66163OV
G71146HJ
G75983OB
G70441OD
G83646BJ
G04657PL
G27058EU
G45495MK
G84452RH
G83460ZZ
G51640FO
G91636VS
G42962KI
G44215PV
G80920RR
G23863VK
G90659AW
G62765YT
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cross-presentation of particulate exogenous antigens (phagosomes) | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| IRAK4 deficiency (TLR2/4) | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Intracellular metabolism of fatty acids regulates insulin secretion | Homo sapiens |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | Homo sapiens |
| MyD88 deficiency (TLR2/4) | Homo sapiens |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| PPARA activates gene expression | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111046 | platelet-type bleeding disorder 10 | |
| DOID:12365 | malaria | |
| DOID:12554 | hemolytic-uremic syndrome | |
| DOID:2218 | blood platelet disease | |
| DOID:2957 | pulmonary tuberculosis | |
| DOID:8398 | osteoarthritis | |
| DOID:9182 | pemphigus | |
| DOID:9352 | type 2 diabetes mellitus |
