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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transforming growth factor beta-1 proprotein
Summary
- UniProt ID
- P17246
- Gene Symbol
-
- Tgfb1
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P17246
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Growth factor
- Mitogen
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| blood microparticle |
| nucleus |
| extracellular space |
| cytoplasm |
| microvillus |
| secretory granule |
| axon |
| extracellular matrix |
| collagen-containing extracellular matrix |
| GO Term |
|---|
| type III transforming growth factor beta receptor binding |
| deubiquitinase activator activity |
Sequence
MPPSGLRLLPLLLPLPWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAIYDKTKDITHSIYMFFNTSDIREAVPEPPLLSRAELRLQRFKSTVEQHVELYQKYSNNSWRYLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNVLHVEINGISPKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Rattus norvegicus |
| Downregulation of TGF-beta receptor signaling | Rattus norvegicus |
| Molecules associated with elastic fibres | Rattus norvegicus |
| Platelet degranulation | Rattus norvegicus |
| RUNX3 regulates CDKN1A transcription | Rattus norvegicus |
| RUNX3 regulates p14-ARF | Rattus norvegicus |
| Regulation of RUNX3 expression and activity | Rattus norvegicus |
| Syndecan interactions | Rattus norvegicus |
| TGF-beta receptor signaling activates SMADs | Rattus norvegicus |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Rattus norvegicus |
