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Vascular endothelial growth factor receptor 1

Summary

UniProt ID

P17948

Gene Symbol

FLT1
FLT
FRT
VEGFR1

Organism

Homo sapiens (human)

External Links

GlyConnect

GlyGen

P17948

PubChem

P17948

The Human Metabolome Database

HMDBP01462

The O-GlcNAc Database

P17948

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Angiogenesis
Cell membrane
Chemotaxis
Cytoplasm
Developmental protein
Differentiation
Direct protein sequencing
Disulfide bond
Endosome
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 21 in total

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GO Term
positive regulation of phospholipase C activity
positive regulation of MAPK cascade
cellular response to vascular endothelial growth factor stimulus
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cell population proliferation
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
positive regulation of cell migration
positive regulation of angiogenesis

Displaying **all 6** entries
GO Term
endosome
focal adhesion
extracellular space
plasma membrane
actin cytoskeleton
receptor complex

Displaying **all 5** entries
GO Term
transmembrane receptor protein tyrosine kinase activity
vascular endothelial growth factor receptor activity
ATP binding
growth factor binding
placental growth factor receptor activity

Annotation information from UniProt.

Sequence

MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKMASTLVVADSRISGIYICIASNKVGTVGRNISFYITDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFIRKMKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEKMEPGLEQGKKPRLDSVTSSESFASSGFQEDKSLSDVEEEEDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKESISAPKFNSGSSDDVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTWTDSKPKASLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIACCSPPPDYNSVVLYSTPPI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	GlyTouCan ID	Source
100	N-linked (GlcNAc...) asparagine	G62765YT	UniProt GlyGen
164	N-linked (GlcNAc...) asparagine	G70232NH G57776ZS G86880BF G28622IK G92135MA G34989PA G43669FQ G45395BF G43223CG G10846ZT G00273SJ G08918WF G87661QW G83646BJ G76295SF G46691LC G27126ED G27058EU G84452RH G83460ZZ G41071NU G70619PT G59626AS G80920RR G01485JJ G42124LM G90659AW G62765YT	UniProt GlyGen GlyConnect
196	N-linked (GlcNAc...) asparagine	G80075MS G57776ZS G45395BF G43223CG G08918WF G61256FT G87661QW G76295SF G46691LC G27058EU G59626AS G80920RR G01485JJ G42124LM G90659AW G62765YT G14669DU G28681TP	UniProt GlyGen GlyConnect
251	N-linked (GlcNAc...) asparagine	G86880BF G27947YN G45395BF G10819WX G40926MX G08918WF G00912UN G92551JA G61256FT G83646BJ G04657PL G27058EU G10488MI G60033FS G41071NU G86182NS G70619PT G06356OH G59626AS G80920RR G01485JJ G65184UU G42124LM G90659AW G77547TA G45504EY G37399XV G83633GK G62765YT G72790NZ G10486CT G28541PG G95865ZB G31852PQ G72787SB G35029YA G57776ZU	UniProt GlyGen GlyConnect
323	N-linked (GlcNAc...) asparagine	G06356OH G59626AS G80920RR G10486CT G14669DU G28681TP	UniProt GlyGen GlyConnect
402	N-linked (GlcNAc...) asparagine	G40834TG G08918WF G00912UN G86182NS G70619PT G59626AS G90659AW G83633GK G62765YT G72790NZ G10486CT	UniProt GlyGen
417	N-linked (GlcNAc...) asparagine		UniProt GlyGen
474	N-linked (GlcNAc...) asparagine	G33609NS G39446WN	UniProt GlyGen GlyConnect
547	N-linked (GlcNAc...) asparagine	G00912UN G83646BJ G27058EU G70619PT G59626AS G01650EU G80920RR G90659AW G37399XV G62765YT G10486CT G28541PG G95865ZB G31852PQ G39446WN G41247ZX G02815KT G49151OV	UniProt GlyGen
597	N-linked (GlcNAc...) asparagine		UniProt GlyGen