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Protein serrate
Summary
- UniProt ID
- P18168
- Gene Symbol
-
- Bd
- CG6127
- Ser
- Gene ID
- 43275
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- 3D-structure
- Developmental protein
- Differentiation
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cell surface |
| apical plasma membrane |
| axolemma |
| apical cortex |
| GO Term |
|---|
| Notch binding |
| calcium ion binding |
| glycosphingolipid binding |
| receptor ligand activity |
Sequence
MFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLPSTIRDCRSLKSACNLIALILILLVHKISAAGNFELEILEISNTNSHLLNGYCCGMPAELRATKTIGCSPCTTAFRLCLKEYQTTEQGASISTGCSFGNATTKILGGSSFVLSDPGVGAIVLPFTFRWTKSFTLILQALDMYNTSYPDAERLIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPCATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECATSPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCLEGHCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSATTTTTTTTTATTTRKMAKPSGLPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMPGAPDKALQPHCRCAPGWTGLFCAEAIDQCRGQPCHNGGTCESGAGWFRCVCAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCEILLSDPKSACQNASNTISPYTALNRSQNWLDIALTGRTEDDENCNACVCENGTSRCTNLWCGLPNCYKVDPLSKSSNLSGVCKQHEVCVPALSETCLSSPCNVRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVGKGASVEGLCSLVRVLLAAQLIKKPASTFGQDPGMLMVLCDLKTGTNDTVELTVSSSKLNDPQLPVAVGLLGELLSFRQLNGIQRRKELELQHAKLAALTSIVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFISLYWKQRLAYRTSSGMNLTPSLDALRHEEEKSNNLQNEENLRRYTNPLKGSTSSLRAATGMELSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQILLHKTQNSDMRKNTVGSLDSPRKDFGKRSINCKSMPPSSGDEGSDVLATTVMV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 148 | N-linked (GlcNAc...) asparagine |
|
||
| 192 | N-linked (GlcNAc...) asparagine |
|
||
| 243 | N-linked (GlcNAc...) asparagine |
|
||
| 327 | N-linked (GlcNAc...) asparagine |
|
||
| 408 | N-linked (GlcNAc...) asparagine |
|
||
| 448 | N-linked (GlcNAc...) asparagine |
|
||
| 554 | N-linked (GlcNAc...) asparagine |
|
||
| 735 | N-linked (GlcNAc...) asparagine |
|
||
| 961 | N-linked (GlcNAc...) asparagine |
|
||
| 973 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| NOTCH4 Activation and Transmission of Signal to the Nucleus | Drosophila melanogaster |
| Negative regulation of NOTCH4 signaling | Drosophila melanogaster |
| Pre-NOTCH Processing in Golgi | Drosophila melanogaster |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12930 | dilated cardiomyopathy |
