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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 3
Summary
- UniProt ID
- P18460
- Gene Symbol
-
- FGFR3
- CEK2
- Organism
- Gallus gallus (chicken)
External Links
- PubChem
- P18460
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| receptor complex |
| GO Term |
|---|
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
Sequence
MRAAWGSVWCLCLAAAVGALPAARRRGAERSGGQAAEYLRSETAFLEELVFGSGDTIELSCNTQSSSVSVFWFKDGIGIAPSNRTHIGQKLLKIINVSYDDSGLYSCKPRHSNEVLGNFTVRVTDSPSSGDDEDDDDESEDTGVPFWTRPDKMEKKLLAVPAANTVRFRCPAGGNPTPTIYWLKNGKEFKGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKYGNIRHTYQLDVLERSPHRPILQAGLPANQTVVVGSNVEFHCKVYSDAQPHIQWLKHVEVNGSKYGPDGTPYVTVLKTAGVNTTDKELEILYLRNVTFEDAGEYTCLAGNSIGFSHHSAWLTVLPAEELMEMDDSGSVYAGILSYGTGLVLFILVLVIVIICRMKMPNKKAMNTTTVQKVSKFPLKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLTLGKPLGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLTMTSTDEYLDLSVPFEQYSPAGQDTHSTCSSGDDSVFAHDLLPDEPCLPKHVPCNGVIRT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 83 | N-linked (GlcNAc...) asparagine |
|
||
| 96 | N-linked (GlcNAc...) asparagine |
|
||
| 118 | N-linked (GlcNAc...) asparagine |
|
||
| 219 | N-linked (GlcNAc...) asparagine |
|
||
| 256 | N-linked (GlcNAc...) asparagine |
|
||
| 288 | N-linked (GlcNAc...) asparagine |
|
||
| 309 | N-linked (GlcNAc...) asparagine |
|
||
| 322 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR3b ligand binding and activation | Gallus gallus |
| FGFR3c ligand binding and activation | Gallus gallus |
| FRS-mediated FGFR3 signaling | Gallus gallus |
| Negative regulation of FGFR3 signaling | Gallus gallus |
| PI-3K cascade:FGFR3 | Gallus gallus |
| PI3K Cascade | Gallus gallus |
| PI3K/AKT Signaling | Gallus gallus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Gallus gallus |
| Phospholipase C-mediated cascade; FGFR3 | Gallus gallus |
| RAF/MAP kinase cascade | Gallus gallus |
