Fibroblast growth factor receptor 3

Summary
UniProt ID
P18460
Gene Symbol
  • FGFR3
  • CEK2
Organism
Gallus gallus (chicken)
PubChem
P18460
Annotation
Keyword
  • ATP-binding
  • Apoptosis
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
Gene Ontology (GO)
Sequence
MRAAWGSVWCLCLAAAVGALPAARRRGAERSGGQAAEYLRSETAFLEELVFGSGDTIELSCNTQSSSVSVFWFKDGIGIAPSNRTHIGQKLLKIINVSYDDSGLYSCKPRHSNEVLGNFTVRVTDSPSSGDDEDDDDESEDTGVPFWTRPDKMEKKLLAVPAANTVRFRCPAGGNPTPTIYWLKNGKEFKGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKYGNIRHTYQLDVLERSPHRPILQAGLPANQTVVVGSNVEFHCKVYSDAQPHIQWLKHVEVNGSKYGPDGTPYVTVLKTAGVNTTDKELEILYLRNVTFEDAGEYTCLAGNSIGFSHHSAWLTVLPAEELMEMDDSGSVYAGILSYGTGLVLFILVLVIVIICRMKMPNKKAMNTTTVQKVSKFPLKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLTLGKPLGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLTMTSTDEYLDLSVPFEQYSPAGQDTHSTCSSGDDSVFAHDLLPDEPCLPKHVPCNGVIRT
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
83 N-linked (GlcNAc...) asparagine
96 N-linked (GlcNAc...) asparagine
118 N-linked (GlcNAc...) asparagine
219 N-linked (GlcNAc...) asparagine
256 N-linked (GlcNAc...) asparagine
288 N-linked (GlcNAc...) asparagine
309 N-linked (GlcNAc...) asparagine
322 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 11 in total
Pathway Name Organism
FGFR3b ligand binding and activation Gallus gallus
FGFR3c ligand binding and activation Gallus gallus
FRS-mediated FGFR3 signaling Gallus gallus
Negative regulation of FGFR3 signaling Gallus gallus
PI-3K cascade:FGFR3 Gallus gallus
PI3K Cascade Gallus gallus
PI3K/AKT Signaling Gallus gallus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Gallus gallus
Phospholipase C-mediated cascade; FGFR3 Gallus gallus
RAF/MAP kinase cascade Gallus gallus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024