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MIRAGE
Fibroblast growth factor receptor 2
Summary
- UniProt ID
- P18461
- Gene Symbol
-
- CEK3
- FGFR2
- Gene ID
- 396259
- Organism
- Gallus gallus (chicken)
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
| Golgi apparatus |
| GO Term |
|---|
| transmembrane receptor protein tyrosine kinase signaling pathway |
| apoptotic process |
| positive regulation of cell population proliferation |
Sequence
MVSWDSGCLICLVVVTMAGLSLARPSFNLVVEDATLEPEEPPTKYQISQPDVHSALPGEPLELRCQLKDAVMISWTKDGVPLGPDNRTVIIGEYLQIKDASPRDSGLYACTAIRTLDSDTLYFIVNVTDALSSGDDEDDNDGSEDFVNDSNQMRAPYWTHTDKMEKRLHAVPAANTVKFRCPAMGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCIVENQYGSINHTYHLDVVERSPHRPILQAGLPANASAVVGGDVEFVCKVYSDAQPHIQWIKHVERNGSKYGPDGLPYLQVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHTAWLTVLPAPEKEKEFPTSPDYLEIAIYCIGVFLIACMVLTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSADSSSSMNSNTPLVRITTRLSSTADAPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSGPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPKYQHMNGSVKT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 86 | N-linked (GlcNAc...) asparagine |
|
||
| 126 | N-linked (GlcNAc...) asparagine |
|
||
| 148 | N-linked (GlcNAc...) asparagine |
|
||
| 230 | N-linked (GlcNAc...) asparagine |
|
||
| 243 | N-linked (GlcNAc...) asparagine |
|
||
| 267 | N-linked (GlcNAc...) asparagine |
|
||
| 299 | N-linked (GlcNAc...) asparagine |
|
||
| 320 | N-linked (GlcNAc...) asparagine |
|
||
| 333 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Gallus gallus |
| FGFR2c ligand binding and activation | Gallus gallus |
| FRS-mediated FGFR2 signaling | Gallus gallus |
| Negative regulation of FGFR2 signaling | Gallus gallus |
| PI-3K cascade:FGFR2 | Gallus gallus |
| PI3K Cascade | Gallus gallus |
| PI3K/AKT Signaling | Gallus gallus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Gallus gallus |
| Phospholipase C-mediated cascade; FGFR2 | Gallus gallus |
| RAF/MAP kinase cascade | Gallus gallus |
