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5-hydroxytryptamine receptor 1A

Summary

UniProt ID

P19327

Gene Symbol

5ht1a
Htr1a

Gene ID

24473

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P19327
Re-Glyco: P19327

Annotation

Keyword

Behavior
Cell membrane
Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
plasma membrane
GABA-ergic synapse
dendrite
neuronal cell body
presynaptic membrane
axon hillock

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 23 in total

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GO Term
regulation of serotonin secretion
regulation of hormone secretion
positive regulation of microtubule depolymerization
behavioral response to nicotine
regulation of dopamine metabolic process
serotonin metabolic process
response to morphine
NMDA glutamate receptor clustering
G protein-coupled serotonin receptor signaling pathway
response to glycoside

Displaying **all 8** entries
GO Term
signaling receptor binding
Gi/o-coupled serotonin receptor activity
serotonin receptor activity
neurotransmitter receptor activity
receptor-receptor interaction
G-protein alpha-subunit binding
G protein-coupled serotonin receptor activity
serotonin binding

Annotation information from UniProt.

Sequence

MDVFSFGQGNNTTASQEPFGTGGNVTSISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
10	N-linked (GlcNAc...) asparagine	UniProt
11	N-linked (GlcNAc...) asparagine	UniProt
24	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Serotonin receptors	Rattus norvegicus

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:14330	Parkinson's disease	Alliance of Genome Resources
DOID:1574	alcohol use disorder	Alliance of Genome Resources
DOID:594	panic disorder	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements