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MIRAGE
Microtubule-associated protein tau
Summary
- UniProt ID
- P19332
- Gene Symbol
-
- Mapt
- Mtapt
- Tau
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Cell membrane
- Cell projection
- Cytoskeleton
- Direct protein sequencing
- Disulfide bond
- Isopeptide bond
- Methylation
- Microtubule
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| tubulin complex |
| neurofibrillary tangle |
| cytoplasmic ribonucleoprotein granule |
| extracellular region |
| nucleus |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| microtubule lateral binding |
| DNA binding |
| microtubule binding |
| SH3 domain binding |
| enzyme binding |
| protein kinase binding |
| apolipoprotein binding |
| identical protein binding |
| protein-containing complex binding |
| protein-folding chaperone binding |
Sequence
MAEPRQEFDTMEDQAGDYTMLQDQEGDMDHGLKESPPQPPADDGSEEPGSETSDAKSTPTAEDVTAPLVEERAPDKQATAQSHTEIPEGTTAEEAGIGDTPNMEDQAAGHVTQEPQKVEIFSQSLLVEPGRREGQAPDSGISDWTHQQVPSMSGAPLPPQGLREATHQPLGTRPEDVERSHPASELLWQESPQKEAWGKDRLGSEEEVDEDITMDESSQESPPSQASLAPGTATPQARSVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQASPPEGPGTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVHIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Caspase-mediated cleavage of cytoskeletal proteins | Rattus norvegicus |
| PKR-mediated signaling | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080855 | Parkinsonism | |
| DOID:0081292 | traumatic brain injury | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1561 | cognitive disorder | |
| DOID:1826 | epilepsy | |
| DOID:2316 | brain ischemia | |
| DOID:3525 | middle cerebral artery infarction | |
| DOID:680 | tauopathy | |
| DOID:8725 | vascular dementia | |
| DOID:9970 | obesity |
