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Hexokinase-1

Summary

UniProt ID

P19367

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlyGen: P19367
PubChem: P19367
The Human Metabolome Database: HMDBP00215
The O-GlcNAc Database: P19367
RaftProt: P19367
O-GlcNAcAtlas: P19367

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Allosteric enzyme
Alternative splicing
Charcot-Marie-Tooth disease
Cytoplasm
Direct protein sequencing
Disease variant
Glycolysis
Inflammatory response
Innate immunity
Intellectual disability
Kinase
Mitochondrion outer membrane
Neurodegeneration
Phosphoprotein
Reference proteome
Repeat
Retinitis pigmentosa

Gene Ontology (GO)

Displaying entries **1 - 10** of 14 in total

1

2

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GO Term
intracellular glucose homeostasis
positive regulation of cytokine production involved in immune response
glucose metabolic process
inflammatory response
innate immune response
positive regulation of interleukin-1 beta production
canonical glycolysis
glycolytic process
carbohydrate phosphorylation
glucose 6-phosphate metabolic process

Displaying **all 4** entries
GO Term
cytosol
mitochondrion
membrane raft
mitochondrial outer membrane

Displaying **all 8** entries
GO Term
glucose binding
mannokinase activity
peptidoglycan binding
glucosamine kinase activity
glucokinase activity
hexokinase activity
ATP binding
fructokinase activity

Annotation information from UniProt.

Sequence

MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites