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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Inter-alpha-trypsin inhibitor heavy chain H2
Summary
- UniProt ID
- P19823
- Gene Symbol
-
- ITIH2
- IGHEP2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Direct protein sequencing
- Disulfide bond
- Gamma-carboxyglutamic acid
- Phosphoprotein
- Proteoglycan
- Reference proteome
- Secreted
- Serine protease inhibitor
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| hyaluronan metabolic process |
| GO Term |
|---|
| endoplasmic reticulum lumen |
| extracellular region |
| collagen-containing extracellular matrix |
| extracellular exosome |
| blood microparticle |
| GO Term |
|---|
| endopeptidase inhibitor activity |
| serine-type endopeptidase inhibitor activity |
| hyaluronic acid binding |
Sequence
MKRLTCFFICFFLSEVSGFEIPINGLSEFVDYEDLVELAPGKFQLVAENRRYQRSLPGESEEMMEEVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVISKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSKVVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQKNICFNIDSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 96 |
|
|||
| 118 | N-linked (GlcNAc...) (complex) asparagine |
|
||
| 445 | N-linked (GlcNAc...) asparagine |
|
||
| 482 |
|
|||
| 483 |
|
|||
| 484 |
|
|||
| 601 |
|
|||
| 652 |
|
|||
| 665 |
|
|||
| 666 | O-linked (GalNAc...) threonine; partial |
G40574BA
G00912UN
G90787TS
G38663NM
G37881RL
G63980BQ
G04854VP
G94470IW
G40834TG
G45395BF
G07246CJ
G85554PZ
G43223CG
G58954YZ
G31986NC
G26330YA
G10846ZT
G82830MN
G08918WF
G47737VJ
G75983OB
G42358LZ
G48414YA
G95660LN
G11911BT
G46691LC
G04657PL
G46524LG
G41071NU
G72747WU
G70619PT
G06356OH
G59626AS
G65835SY
G08290VR
G01650EU
G37399XV
G10486CT
G22140GZ
G50045TK
G95865ZB
G06110VR
G28681TP
G37995HC
G49108TO
G57321FI
G43417UB
G57317CE
G63110FE
G10225UW
G74722FL
G98535LH
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
