GlyCosmos Portal

Submissions

Mannose-binding protein A

Summary

UniProt ID

P19999

Gene Symbol

Mbl1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P19999

Annotation

Keyword

3D-structure
Calcium
Collagen
Complement activation lectin pathway
Complement pathway
Direct protein sequencing
Disulfide bond
Glycoprotein
Hydroxylation
Mannose-binding
Metal-binding
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
surfactant homeostasis
positive regulation of phagocytosis
killing by host of symbiont cells
complement activation, lectin pathway
defense response to Gram-positive bacterium
complement activation, classical pathway
protein homotrimerization

Displaying **all 3** entries
GO Term
multivesicular body
collagen trimer
extracellular space

Displaying **all 10** entries
GO Term
protease binding
calcium ion binding
polysaccharide binding
calcium-dependent protein binding
identical protein binding
protein homodimerization activity
oligosaccharide binding
mannose binding
phosphatidylinositol-4-phosphate binding
calcium-dependent carbohydrate binding

Annotation information from UniProt.

Sequence

MLLLPLLVLLCVVSVSSSGSQTCEETLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGAPGSQGPKGQKGDRGDSRAIEVKLANMEAEINTLKSKLELTNKLHAFSMGKKSGKKFFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQEVAKTSAFLGITDEVTEGQFMYVTGGRLTYSNWKKDEPNDHGSGEDCVTIVDNGLWNDISCQASHTAVCEFPA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	Source
44	O-linked (Gal...) hydroxylysine	10903744 25419660	UniProt GlyGen
47	O-linked (Gal...) hydroxylysine	10903744 25419660	UniProt GlyGen
79	O-linked (Gal...) hydroxylysine	25419660	UniProt GlyGen
82	O-linked (Gal...) hydroxylysine	25419660	UniProt GlyGen