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MIRAGE
Endothelin-2

Summary
UniProt ID
P20800
Gene Symbol
  • EDN2
Gene ID
1907
Organism
Homo sapiens (human)
GlyGen
P20800
PubChem
P20800
Re-Glyco
P20800
Annotation
Keyword
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disulfide bond
  • Reference proteome
  • Secreted
  • Signal
  • Vasoconstrictor
Gene Ontology (GO)
Displaying all 2 entries
GO Term
extracellular region
extracellular space
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
endothelin B receptor binding
hormone activity
Annotation information from UniProt.
Sequence
MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
113
116
123
136
139
Feature
204060801001201401601178
20406080100120140160MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR
Domains & sites
PTM
ProtVista
20406080100120140160MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
G alpha (q) signalling events Homo sapiens
Peptide ligand-binding receptors Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:10763 hypertension
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025