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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement C2
Summary
- UniProt ID
- P21180
- Gene Symbol
-
- C2
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003473
- PubChem
- P21180
Annotation
- Keyword
-
- Alternative splicing
- Complement pathway
- Disulfide bond
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| extracellular exosome |
| classical-complement-pathway C3/C5 convertase complex |
| GO Term |
|---|
| metal ion binding |
| serine-type endopeptidase activity |
Sequence
MAPLLALFYLLQLGPGLAALFCNQNVNITGGNFTLSHGWAPGSLLIYSCPLGRYPSPAWRKCQSNGQWLTPRSSSHHTLRSSRMVKAVCKPVRCLAPSSFENGIYFPRLVSYPVGSNVSFECEQDFTLRGSPVRYCRPNGLWDGETAVCDNGASHCPNPGISVGTARTGLNFDLGDKVRYRCSSSNMVLTGSAERECQSNGVWSGSEPICRQPYSYDFPEDVASALDTSLTNLLGATNPTQNLLTKSLGRKIIIQRSGHLNLYLLLDASQSVTEKDFDIFKKSAELMVERIFSFEVNVSVAIITFASQPKTIMSILSERSQDVTEVITSLDSASYKDHENATGTNTYEVLIRVYSMMQSQMDRLGMETSAWKEIRHTIILLTDGKSNMGDSPKKAVTRIRELLSIEQNRDDYLDIYAIGVGKLDVDWKELNELGSKKDGERHAFILQDAKALQQIFEHMLDVSKLTDTICGVGNMSANASDQERTPWQVTFKPKSKETCQGSLISDQWVLTAAHCFHDIQMEDHHLWRVNVGDPTSQHGKEFLVEDVIIAPGFNVHAKRKQGISEFYADDIALLKLSRKVKMSTHARPICLPCTVGANMALRRSPGSTCKDHETELLSQQKVPAHFVALNGNRLNINLRTGPEWTRCIQAVSQNKNIFPSLTNVSEVVTDQFLCSGMEEEDDNPCKGESGGAVFLGRRYRFFQVGLVSWGLFDPCHGSSNKNLRKKPPRGVLPRDFHISLFRLQPWLRQHLDGVLDFLPL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 27 | N-linked (GlcNAc...) asparagine |
|
||
| 32 | N-linked (GlcNAc...) asparagine |
|
||
| 117 | N-linked (GlcNAc...) asparagine |
|
||
| 297 | N-linked (GlcNAc...) asparagine |
|
||
| 340 | N-linked (GlcNAc...) asparagine |
|
||
| 474 | N-linked (GlcNAc...) asparagine |
|
||
| 478 | N-linked (GlcNAc...) asparagine |
|
||
| 663 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of C3 and C5 | Mus musculus |
| Initial triggering of complement | Mus musculus |
| Regulation of Complement cascade | Mus musculus |
