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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cytoplasmic aconitate hydratase
Summary
- UniProt ID
- P21399
- Gene Symbol
-
- ACO1
- IREB1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P21399
- PubChem
- P21399
- The Human Metabolome Database
- HMDBP00726
- The O-GlcNAc Database
- P21399
- RaftProt
- P21399
Annotation
- Keyword
-
- 3D-structure
- 4Fe-4S
- Cytoplasm
- Direct protein sequencing
- Lyase
- Phosphoprotein
- RNA-binding
- Reference proteome
- Tricarboxylic acid cycle
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| Golgi apparatus |
| extracellular exosome |
| mitochondrion |
| cytosol |
| endoplasmic reticulum |
| GO Term |
|---|
| RNA binding |
| metal ion binding |
| 3 iron, 4 sulfur cluster binding |
| 4 iron, 4 sulfur cluster binding |
| iron-responsive element binding |
| aconitate hydratase activity |
Sequence
MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 651 |
|
|||
|
|
G90787TS
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Iron uptake and transport | Homo sapiens |
| NADPH regeneration | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4766 | embryoma | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:769 | neuroblastoma | |
| DOID:8398 | osteoarthritis | |
| DOID:8432 | polycythemia | |
| DOID:848 | arthritis | |
| DOID:8893 | psoriasis | |
| DOID:8923 | skin melanoma | |
| DOID:893 | Wilson disease |
