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Mitogen-activated protein kinase 3

Summary

UniProt ID

P21708

Gene Symbol

Mapk3
Erk1
Prkm3

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P21708
PubChem: P21708
The O-GlcNAc Database: P21708

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell cycle
Cell junction
Cytoplasm
Direct protein sequencing
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
apoptotic process
cell cycle
insulin receptor signaling pathway
response to toxic substance
animal organ morphogenesis
neural crest cell development
phosphorylation
cartilage development
cardiac neural crest cell development involved in heart development
protein-containing complex assembly

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GO Term
cytosol
caveola
nucleoplasm
early endosome
late endosome
focal adhesion

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GO Term
protein kinase activity
protein serine/threonine kinase activity
DNA-binding transcription factor binding
identical protein binding
phosphatase binding
phosphotyrosine residue binding
MAP kinase activity
ATP binding
scaffold protein binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERLKELIFQETARFQPGAPEAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 41 in total

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Pathway Name	Organism
Activation of the AP-1 family of transcription factors	Rattus norvegicus
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Rattus norvegicus
ERK/MAPK targets	Rattus norvegicus
ERKs are inactivated	Rattus norvegicus
FCERI mediated MAPK activation	Rattus norvegicus
Frs2-mediated activation	Rattus norvegicus
Gastrin-CREB signalling pathway via PKC and MAPK	Rattus norvegicus
Golgi Cisternae Pericentriolar Stack Reorganization	Rattus norvegicus
Growth hormone receptor signaling	Rattus norvegicus
IFNG signaling activates MAPKs	Rattus norvegicus