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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 1
Summary
- UniProt ID
- P21804
- Gene Symbol
-
- FGFR1
- CEK1
- Organism
- Gallus gallus (chicken)
External Links
- PubChem
- P21804
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
| cytosol |
| GO Term |
|---|
| heparin binding |
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
Sequence
MFTWRCLILWAVLVTATLSAARPAPTLPDQALPKANIEVESHSAHPGDLLQLRCRLRDDVQSINWVRDGVQLPENNRTRITGEEVEVRDAVPEDSGLYACMTNSPSGSETTYFSVNVSDALPSAEDDDDEDDSSSEEKEADNTKPNQAVAPYWTYPEKMEKKLHAVPAAKTVKFKCPSGGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENKYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFVCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGISHHSAWLTVLEATEQSPAMMTSPLYLEIIIYCTGAFLISCMVVTVIIYKMKSTTKKTDFNSQLAVHKLAKSIPLRRQVTVSADSSSSMNSGVMLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLILGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEYLDLSVPLDQYSPGFPATRSSTCSSGEDSVFSHDPLPDEPCLPRCPPHSHGALKRH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 76 | N-linked (GlcNAc...) asparagine |
|
||
| 116 | N-linked (GlcNAc...) asparagine |
|
||
| 225 | N-linked (GlcNAc...) asparagine |
|
||
| 238 | N-linked (GlcNAc...) asparagine |
|
||
| 262 | N-linked (GlcNAc...) asparagine |
|
||
| 294 | N-linked (GlcNAc...) asparagine |
|
||
| 315 | N-linked (GlcNAc...) asparagine |
|
||
| 328 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signaling of activated FGFR1 | Gallus gallus |
| FGFR1b ligand binding and activation | Gallus gallus |
| FGFR1c and Klotho ligand binding and activation | Gallus gallus |
| FGFR1c ligand binding and activation | Gallus gallus |
| FRS-mediated FGFR1 signaling | Gallus gallus |
| Negative regulation of FGFR1 signaling | Gallus gallus |
| PI-3K cascade:FGFR1 | Gallus gallus |
| PI3K Cascade | Gallus gallus |
| PI3K/AKT Signaling | Gallus gallus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Gallus gallus |
