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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Biglycan
Summary
- UniProt ID
- P21809
- Gene Symbol
-
- BGN
- Organism
- Bos taurus (domestic cattle)
External Links
- PubChem
- P21809
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Leucine-rich repeat
- Proteoglycan
- Reference proteome
- Repeat
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| bone development |
| articular cartilage development |
| GO Term |
|---|
| extracellular matrix |
| transport vesicle |
| cell surface |
| sarcolemma |
| extracellular region |
| extracellular space |
| GO Term |
|---|
| extracellular matrix binding |
| glycosaminoglycan binding |
| cytokine binding |
Sequence
MWPLWPLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 42 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 48 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 181 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 199 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 271 |
|
|
||
| 312 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Bos taurus |
| CS/DS degradation | Bos taurus |
| Chondroitin sulfate biosynthesis | Bos taurus |
| Dermatan sulfate biosynthesis | Bos taurus |
| ECM proteoglycans | Bos taurus |
