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Biglycan

Summary
UniProt ID
P21809
Gene Symbol
  • BGN
Gene ID
280733
Organism
Bos taurus (domestic cattle)
PubChem
P21809
Re-Glyco
P21809
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Disulfide bond
  • Extracellular matrix
  • Leucine-rich repeat
  • Proteoglycan
  • Reference proteome
  • Repeat
  • Signal
Gene Ontology (GO)
Displaying all 3 entries
GO Term
extracellular region
extracellular space
transport vesicle
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MWPLWPLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
42 O-linked (Xyl...) (glycosaminoglycan) serine
48 O-linked (Xyl...) (glycosaminoglycan) serine
181 O-linked (Xyl...) (glycosaminoglycan) serine
199 O-linked (Xyl...) (glycosaminoglycan) serine
271
312 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
A tetrasaccharide linker sequence is required for GAG synthesis Bos taurus
CS/DS degradation Bos taurus
Chondroitin sulfate biosynthesis Bos taurus
Dermatan sulfate biosynthesis Bos taurus
ECM proteoglycans Bos taurus
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025