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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Summary
- UniProt ID
- P21912
- Gene Symbol
-
- SDHB
- SDH
- SDH1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 2Fe-2S
- 3D-structure
- 3Fe-4S
- 4Fe-4S
- Acetylation
- Disease variant
- Electron transport
- Host-virus interaction
- Mitochondrion inner membrane
- Oxidoreductase
- Primary mitochondrial disease
- Reference proteome
- Transit peptide
- Tricarboxylic acid cycle
- Gene Ontology (GO)
Sequence
MAAVVALSLRRRLPATTLGGACLQASRGAQTAAATAPRIKKFAIYRWDPDKAGDKPHMQTYEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 35 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Citric acid cycle (TCA cycle) | Homo sapiens |
| Maturation of TCA enzymes and regulation of TCA cycle | Homo sapiens |
| Respiratory electron transport | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8440 | ileus | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050424 | familial adenomatous polyposis | |
| DOID:0050428 | nonepidermolytic palmoplantar keratoderma | |
| DOID:0050430 | multiple endocrine neoplasia type 2A | |
| DOID:0050486 | exanthem | |
| DOID:0050572 | cone-rod dystrophy | |
| DOID:0050657 | Bannayan-Riley-Ruvalcaba syndrome | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050771 | pheochromocytoma |
