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MIRAGE
D(4) dopamine receptor

Summary
UniProt ID
P21917
Gene Symbol
  • DRD4
Gene ID
1815
Organism
Homo sapiens (human)
GlyGen
P21917
PubChem
P21917
The Human Metabolome Database
HMDBP02531
O-GlcNAcAtlas
P21917
Re-Glyco
P21917
Annotation
Keyword
  • 3D-structure
  • Biological rhythms
  • Cell membrane
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Metal-binding
  • Palmitate
  • Reference proteome
  • Repeat
  • Sodium
  • Transmembrane helix
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 6 entries
GO Term
glutamatergic synapse
plasma membrane
membrane
dendrite
postsynapse
centrosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
3 N-linked (GlcNAc...) asparagine
239
245
247
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Dopamine receptors Homo sapiens
G alpha (i) signalling events Homo sapiens
Disease
Displaying entries 1 - 10 of 14 in total
DO ID Disease Name Source
DOID:0050742 nicotine dependence
DOID:1059 intellectual disability
DOID:10939 antisocial personality disorder
DOID:1094 attention deficit hyperactivity disorder
DOID:11119 Gilles de la Tourette syndrome
DOID:11206 opioid abuse
DOID:12399 pathological gambling
DOID:12995 conduct disorder
DOID:1574 alcohol use disorder
DOID:302 substance abuse
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025