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D(4) dopamine receptor

Summary

UniProt ID

P21917

Gene Symbol

DRD4

Organism

Homo sapiens (human)

External Links

GlyGen: P21917
PubChem: P21917
The Human Metabolome Database: HMDBP02531
The O-GlcNAc Database: P21917
O-GlcNAcAtlas: P21917

Annotation

Keyword

3D-structure
Biological rhythms
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Metal-binding
Palmitate
Reference proteome
Repeat
Sodium
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

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GO Term
intracellular calcium ion homeostasis
regulation of dopamine secretion
positive regulation of kinase activity
response to histamine
regulation of dopamine metabolic process
dopamine metabolic process
rhythmic process
negative regulation of protein secretion
negative regulation of synaptic transmission, glutamatergic
negative regulation of voltage-gated calcium channel activity

Displaying **all 6** entries
GO Term
dendrite
postsynapse
glutamatergic synapse
centrosome
plasma membrane
membrane

Displaying entries **1 - 10** of 12 in total

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GO Term
G protein-coupled serotonin receptor activity
metal ion binding
serotonin binding
neurotransmitter receptor activity
dopamine binding
epinephrine binding
norepinephrine binding
potassium channel regulator activity
SH3 domain binding
identical protein binding

Annotation information from UniProt.

Sequence

MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites