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Alpha-2C adrenergic receptor

Summary

UniProt ID

P22086

Gene Symbol

Adra2c

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P22086

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
positive regulation of vasoconstriction
adrenergic receptor signaling pathway
positive regulation of MAPK cascade
negative regulation of uterine smooth muscle contraction
adenylate cyclase-activating adrenergic receptor signaling pathway
G protein-coupled receptor signaling pathway
female pregnancy
platelet activation
positive regulation of neuron differentiation

Displaying **all 8** entries
GO Term
cytoplasm
plasma membrane
axon
postsynaptic membrane
neuronal cell body
axon terminus
postsynaptic density membrane
glutamatergic synapse

Displaying **all 6** entries
GO Term
epinephrine binding
alpha-2A adrenergic receptor binding
protein homodimerization activity
protein heterodimerization activity
alpha2-adrenergic receptor activity
G protein-coupled receptor activity

Annotation information from UniProt.

Sequence

MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
19	N-linked (GlcNAc...) asparagine			UniProt
33	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Adrenaline signalling through Alpha-2 adrenergic receptor	Rattus norvegicus
Adrenaline,noradrenaline inhibits insulin secretion	Rattus norvegicus
Adrenoceptors	Rattus norvegicus
G alpha (i) signalling events	Rattus norvegicus
G alpha (z) signalling events	Rattus norvegicus
Surfactant metabolism	Rattus norvegicus