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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Acetylcholinesterase
Summary
- UniProt ID
- P22303
- Gene Symbol
-
- ACHE
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P22303
- PubChem
- P22303
- The Human Metabolome Database
- HMDBP00524
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood group antigen
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Neurotransmitter degradation
- Nucleus
- Reference proteome
- Secreted
- Serine esterase
- Signal
- Synapse
- Gene Ontology (GO)
| GO Term |
|---|
| osteoblast development |
| acetylcholine catabolic process |
| cell adhesion |
| nervous system development |
| synapse assembly |
| GO Term |
|---|
| side of membrane |
| perinuclear region of cytoplasm |
| synapse |
Sequence
MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 296 | N-linked (GlcNAc...) asparagine | |||
| 381 | N-linked (GlcNAc...) asparagine | |||
| 495 | N-linked (GlcNAc...) asparagine |
|
G83460ZZ
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neurotransmitter clearance | Homo sapiens |
| Synthesis of PC | Homo sapiens |
| Synthesis, secretion, and deacylation of Ghrelin | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060196 | amyotrophic lateral sclerosis type 4 | |
| DOID:0060215 | Balo concentric sclerosis | |
| DOID:0060250 | idiopathic scoliosis | |
| DOID:0060255 | rippling muscle disease 2 | |
| DOID:0060262 | gallbladder disease | |
| DOID:0060306 | Meier-Gorlin syndrome | |
| DOID:0060319 | cardiac arrest | |
| DOID:0060326 | myelomeningocele | |
| DOID:0060578 | Noonan syndrome 1 | |
| DOID:0060672 | Grn-related frontotemporal lobar degeneration with Tdp43 inclusions |
