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UDP-glucuronosyltransferase 1A4

Summary

UniProt ID

P22310

Gene Symbol

UGT1A4
GNT1
UGT1

Organism

Homo sapiens (human)

External Links

GlyConnect

1876

GlyGen

P22310

PubChem

P22310

SwissLipids

SLP:000001872

The Human Metabolome Database

HMDBP00478

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Lipid metabolism
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
cellular glucuronidation
negative regulation of fatty acid metabolic process
bilirubin conjugation
negative regulation of glucuronosyltransferase activity
negative regulation of cellular glucuronidation
vitamin D3 metabolic process
heme catabolic process

Displaying **all 2** entries
GO Term
endoplasmic reticulum
endoplasmic reticulum membrane

Displaying **all 4** entries
GO Term
glucuronosyltransferase activity
enzyme binding
protein homodimerization activity
protein heterodimerization activity

Annotation information from UniProt.

Sequence

MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVVLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNVSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDLDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
119	N-linked (GlcNAc...) asparagine			UniProt GlyGen
142	N-linked (GlcNAc...) asparagine	19159218		UniProt GlyGen
296	N-linked (GlcNAc...) asparagine			UniProt GlyGen
348	N-linked (GlcNAc...) asparagine	19159218	G39188ZX G14669DU	UniProt GlyGen GlyConnect