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Insulin-like growth factor-binding protein 4

Summary

UniProt ID

P22692

Gene Symbol

IGFBP4
IBP4

Organism

Homo sapiens (human)

External Links

GlycoProtDB: GPDB0011617
GlyGen: P22692
PubChem: P22692

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disulfide bond
Glycoprotein
Growth factor binding
Phosphoprotein
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
regulation of cell growth
signal transduction
regulation of glucose metabolic process
MAPK cascade
positive regulation of MAPK cascade
negative regulation of canonical Wnt signaling pathway
response to organic cyclic compound
regulation of insulin-like growth factor receptor signaling pathway
positive regulation of insulin-like growth factor receptor signaling pathway
type B pancreatic cell proliferation

Displaying **all 3** entries
GO Term
endoplasmic reticulum lumen
extracellular region
extracellular space

Displaying **all 3** entries
GO Term
insulin-like growth factor I binding
insulin-like growth factor II binding
signaling receptor binding

Annotation information from UniProt.

Sequence

MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites