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Protein Wnt-5a

Summary

UniProt ID

P22725

Gene Symbol

Wnt5a
Wnt-5a

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003491
GlyGen: P22725
PubChem: P22725

Annotation

Keyword

Alternative splicing
Chondrogenesis
Developmental protein
Differentiation
Direct protein sequencing
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Reference proteome
Signal
Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **141 - 150** of **174** in total

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GO Term
negative regulation of canonical Wnt signaling pathway
activation of GTPase activity
cellular response to molecule of bacterial origin
positive regulation of protein kinase C signaling
planar cell polarity pathway involved in neural tube closure
regulation of postsynaptic specialization assembly
regulation of postsynaptic cytosolic calcium ion concentration
positive regulation of neuron projection arborization
positive regulation of dendrite extension
somitogenesis

Displaying **all 8** entries
GO Term
extracellular region
extracellular space
endoplasmic reticulum lumen
cell surface
Schaffer collateral - CA1 synapse
extracellular matrix
postsynapse
glutamatergic synapse

Displaying **all 6** entries
GO Term
protein domain specific binding
cytokine activity
frizzled binding
receptor tyrosine kinase-like orphan receptor binding
chemoattractant activity involved in axon guidance
signaling receptor binding

Annotation information from UniProt.

Sequence

MKKPIGILSPGVALGTAGGAMSSKFFLMALATFFSFAQVVIEANSWWSLGMNNPVQMSEVYIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
114	N-linked (GlcNAc...) asparagine	17117926	G80920RR	GlycoProtDB UniProt GlyGen
120	N-linked (GlcNAc...) asparagine	17117926		UniProt GlyGen
312	N-linked (GlcNAc...) asparagine	17117926	G07755XJ	GlycoProtDB UniProt GlyGen
326	N-linked (GlcNAc...) asparagine	17117926		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Asymmetric localization of PCP proteins	Mus musculus
Ca2+ pathway	Mus musculus
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
PCP/CE pathway	Mus musculus
TCF dependent signaling in response to WNT	Mus musculus
WNT ligand biogenesis and trafficking	Mus musculus
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	Mus musculus
WNT5A-dependent internalization of FZD4	Mus musculus