Lutropin-choriogonadotropic hormone receptor

Summary
UniProt ID
P22888
Gene Symbol
  • LCGR
  • LGR2
  • LHCGR
  • LHRHR
Gene ID
3973
Organism
Homo sapiens (human)
PubChem
P22888
The Human Metabolome Database
HMDBP02152
Re-Glyco
P22888
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Leucine-rich repeat
  • Palmitate
  • Reference proteome
  • Repeat
  • Signal
  • Sulfation
  • Transmembrane helix
Gene Ontology (GO)
Sequence
MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYTSNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
99 N-linked (GlcNAc...) asparagine
174 N-linked (GlcNAc...) asparagine
195 N-linked (GlcNAc...) asparagine
291 N-linked (GlcNAc...) asparagine
299 N-linked (GlcNAc...) asparagine
313 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
G alpha (s) signalling events Homo sapiens
Hormone ligand-binding receptors Homo sapiens
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:0111545 familial male-limited precocious puberty
DOID:0112259 Leydig cell hypoplasia
DOID:1612 breast cancer
DOID:2277 gonadal disease
DOID:2696 Leydig cell tumor

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025