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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Macrophage mannose receptor 1
Summary
- UniProt ID
- P22897
- Gene Symbol
-
- MRC1
- CLEC13D
- CLEC13DL
- MRC1L1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Endocytosis
- Endosome
- Glycoprotein
- Host cell receptor for virus entry
- Host-virus interaction
- Lectin
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cellular response to type II interferon |
| cellular response to lipopolysaccharide |
| receptor-mediated endocytosis |
| cellular response to interleukin-4 |
| GO Term |
|---|
| endosome membrane |
| cell surface |
| plasma membrane |
| GO Term |
|---|
| virus receptor activity |
| mannose binding |
| transmembrane signaling receptor activity |
| signaling receptor activity |
| cargo receptor activity |
Sequence
MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHCNESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNWNTGDPSGERNDCVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLTTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSPGTSDMKDLVGNIEQNEHSVI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 104 | N-linked (GlcNAc...) asparagine | |||
| 147 |
|
|||
| 344 | N-linked (GlcNAc...) asparagine | |||
| 529 | N-linked (GlcNAc...) asparagine |
|
||
| 790 |
|
|||
| 926 | N-linked (GlcNAc...) asparagine | |||
| 930 | N-linked (GlcNAc...) asparagine |
|
||
| 937 |
|
|||
| 1093 |
|
|||
| 1160 | N-linked (GlcNAc...) asparagine |
G64394MX
G38663NM
G33791AF
G35541EV
G93718GY
G57776ZS
G86795LJ
G56784JY
G87123QX
G79666IR
G08146BT
G22310AV
G45395BF
G83229XP
G71146HJ
G75983OB
G70441OD
G27058EU
G45495MK
G84452RH
G42962KI
G44215PV
G23863VK
G57818FI
G62765YT
G25418HZ
G51413EV
G25451PN
G43417UB
G82830MN
G48414YA
G29068FM
G10019LZ
G40834TG
G46691LC
G04657PL
G90659AW
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cross-presentation of soluble exogenous antigens (endosomes) | Homo sapiens |
| Modulation by Mtb of host immune system | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10264 | mumps | |
| DOID:9970 | obesity | |
| DOID:0014667 | disease of metabolism | |
| DOID:1024 | leprosy | |
| DOID:0040085 | bacterial sepsis | |
| DOID:0050133 | superficial mycosis | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050424 | familial adenomatous polyposis | |
| DOID:0050465 | Muir-Torre syndrome |
