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Metabotropic glutamate receptor 1

Summary

UniProt ID

P23385

Gene Symbol

Grm1
Gprc1a
Mglur1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P23385
PubChem: P23385

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
phospholipase C-activating G protein-coupled glutamate receptor signaling pathway
L-glutamate import across plasma membrane
phospholipase C-activating G protein-coupled receptor signaling pathway
positive regulation of MAPK cascade
cellular response to electrical stimulus
G protein-coupled receptor signaling pathway
G protein-coupled glutamate receptor signaling pathway
chemical synaptic transmission
locomotory behavior
membrane depolarization

Displaying entries **1 - 10** of 14 in total

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GO Term
postsynaptic density
G protein-coupled receptor dimeric complex
G protein-coupled receptor homodimeric complex
presynaptic membrane
dendritic spine
Schaffer collateral - CA1 synapse
postsynaptic density membrane
nucleus
plasma membrane
axon

Displaying **all 8** entries
GO Term
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
nuclear estrogen receptor binding
PLC activating G protein-coupled glutamate receptor activity
adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
G protein-coupled receptor activity
glutamate receptor activity
G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Annotation information from UniProt.

Sequence

MVRLLLIFFPMIFLEMSILPRMPDRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGMVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEFVQDEFTCRACDLGWWPNAELTGCEPIPVRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGGRQAPKGQHVWQRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDASTKTLYNVEEEDNTPSAHFSPPSSPSMVVHRRGPPVATTPPLPPHLTAEETPLFLADSVIPKGLPPPLPQQQPQQPPPQQPPQQPKSLMDQLQGVVTNFGSGIPDFHAVLAGPGTPGNSLRSLYPPPPPPQHLQMLPLHLSTFQEESISPPGEDIDDDSERFKLLQEFVYEREGNTEEDELEEEEDLPTASKLTPEDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	Source
98	N-linked (GlcNAc...) asparagine	11069170	UniProt GlyGen
223	N-linked (GlcNAc...) asparagine	11069170	UniProt GlyGen
397	N-linked (GlcNAc...) asparagine		UniProt GlyGen
515	N-linked (GlcNAc...) asparagine		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Class C/3 (Metabotropic glutamate/pheromone receptors)	Rattus norvegicus
G alpha (q) signalling events	Rattus norvegicus
Neurexins and neuroligins	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements