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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Receptor tyrosine-protein kinase let-23
Summary
- UniProt ID
- P24348
- Gene Symbol
-
- let-23
- kin-7
- Organism
- Caenorhabditis elegans
External Links
- GlycoProtDB
- GPDB0000498
- PubChem
- P24348
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Developmental protein
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| ovulation |
| determination of adult lifespan |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| positive regulation of vulval development |
| vulval cell fate specification |
| GO Term |
|---|
| cell-cell junction |
| receptor complex |
| basolateral plasma membrane |
| apical plasma membrane |
| lateral plasma membrane |
| basal plasma membrane |
Sequence
MRYPPSIGSILLIIPIFLTFFGNSNAQLWKRCVSPQDCLCSGTTNGISRYGTGNILEDLETMYRGCRRVYGNLEITWIEANEIKKWRESTNSTVDPKNEDSPLKSINFFDNLEEIRGSLIIYRANIQKISFPRLRVIYGDEVFHDNALYIHKNDKVHEVVMRELRVIRNGSVTIQDNPKMCYIGDKIDWKELLYDPDVQKVETTNSHQHCYQNGKSMAKCHESCNDKCWGSGDNDCQRVYRSVCPKSCSQCFYSNSTSSYECCDSACLGGCTGHGPKNCIACSKYELDGICIETCPSRKIFNHKTGRLVFNPDGRYQNGNHCVKECPPELLIENDVCVRHCSDGHHYDATKDVRECEKCRSSSCPKICTVDGHLTNETLKNLEGCEQIDGHLIIEHAFTYEQLKVLETVKIVSEYITIVQQNFYDLKFLKNLQIIEGRKLHNVRWALAIYQCDDLEELSLNSLKLIKTGAVLIMKNHRLCYVSKIDWSSIITSKGKDNKPSLAIAENRDSKLCETEQRVCDKNCNKRGCWGKEPEDCLECKTWKSVGTCVEKCDTKGFLRNQTSMKCERCSPECETCNGLGELDCLTCRHKTLYNSDFGNRMECVHDCPVSHFPTQKNVCEKCHPTCYDNGCTGPDSNLGYGGCKQCKYAVKYENDTIFCLQSSGMNNVCVENDLPNYYISTYDTEGVIETHCEKCSISCKTCSSAGRNVVQNKCVCKHVEYQPNPSERICMDQCPVNSFMVPDTNNTVCKKCHHECDQNYHCANGQSTGCQKCKNFTVFKGDIAQCVSECPKNLPFSNPANGECLDYDIASRQRKTRMVIIGSVLFGFAVMFLFILLVYWRCQRIGKKLKIAEMVDMPELTPIDASVRPNMSRICLIPSSELQTKLDKKLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTDQSQTDEMLEEATNMFRLRHDNLLKIIGFCMHDDGLKIVTIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQRVVHRDLATRNVLVKKFNHVEITDFGLSKILKHDADSITIKSGKVAIKWLAIEIFSKHCYTHASDVWAFGVTCWEIITFGQSPYQGMSTDSIHNFLKDGNRLSQPPNCSQDLYQELLRCWMADPKSRPGFEILYERFKEFCKVPQLFLENSNKISESDLSAEERFQTERIREMFDGNIDPQMYFDQGSLPSMPSSPTSMATFTIPHGDLMNRMQSVNSSRYKTEPFDYGSTAQEDNSYLIPKTKEVQQSAVLYTAVTNEDGQTELSPSNGDYYNQPNTPSSSSGYYNEPHLKTKKPETSEEAEAVQYENEEVSQKETCL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 91 | N-linked (GlcNAc...) asparagine |
|
||
| 169 | N-linked (GlcNAc...) asparagine |
|
||
| 255 | N-linked (GlcNAc...) asparagine |
|
||
| 376 | N-linked (GlcNAc...) asparagine |
|
||
| 561 | N-linked (GlcNAc...) asparagine |
|
||
| 655 | N-linked (GlcNAc...) asparagine |
|
||
| 746 | N-linked (GlcNAc...) asparagine |
|
||
| 776 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Caenorhabditis elegans |
| Clathrin-mediated endocytosis | Caenorhabditis elegans |
| Downregulation of ERBB2 signaling | Caenorhabditis elegans |
| Downregulation of ERBB4 signaling | Caenorhabditis elegans |
| Drug-mediated inhibition of ERBB2 signaling | Caenorhabditis elegans |
| EGFR Transactivation by Gastrin | Caenorhabditis elegans |
| EGFR downregulation | Caenorhabditis elegans |
| ERBB2 Activates PTK6 Signaling | Caenorhabditis elegans |
| ERBB2 Regulates Cell Motility | Caenorhabditis elegans |
| Extra-nuclear estrogen signaling | Caenorhabditis elegans |
