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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
DNA-directed RNA polymerase II subunit RPB1
Summary
- UniProt ID
- P24928
- Gene Symbol
-
- POLR2A
- POLR2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P24928
- PubChem
- P24928
- The Human Metabolome Database
- HMDBP00739
- The O-GlcNAc Database
- P24928
- O-GlcNAcAtlas
- P24928
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Chromosome
- Cytoplasm
- DNA-binding
- DNA-directed RNA polymerase
- Disease variant
- Host-virus interaction
- Hydrolase
- Intellectual disability
- Isopeptide bond
- Magnesium
- Metal-binding
- Methylation
- Nucleus
- Phosphoprotein
- RNA-directed RNA polymerase
- Reference proteome
- Repeat
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| nucleus |
| chromosome |
| cytoplasm |
| RNA polymerase II, core complex |
| GO Term |
|---|
| zinc ion binding |
| hydrolase activity |
| RNA polymerase II activity |
| DNA-directed 5'-3' RNA polymerase activity |
| microfibril binding |
| magnesium ion binding |
| DNA binding |
| RNA binding |
| RNA-dependent RNA polymerase activity |
| kinase binding |
Sequence
MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPASPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN
Glycosylation Sites
G41247ZX
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Abortive elongation of HIV-1 transcript in the absence of Tat | Homo sapiens |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | Homo sapiens |
| Dual incision in TC-NER | Homo sapiens |
| Estrogen-dependent gene expression | Homo sapiens |
| FGFR2 alternative splicing | Homo sapiens |
| Formation of HIV elongation complex in the absence of HIV Tat | Homo sapiens |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | Homo sapiens |
| Formation of RNA Pol II elongation complex | Homo sapiens |
| Formation of TC-NER Pre-Incision Complex | Homo sapiens |
| Formation of the Early Elongation Complex | Homo sapiens |
