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Tumor necrosis factor receptor superfamily member 6

Summary

UniProt ID

P25445

Gene Symbol

FAS
APT1
FAS1
TNFRSF6

Organism

Homo sapiens (human)

External Links

GlyConnect

GlyGen

P25445

PubChem

P25445

RaftProt

P25445

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Calmodulin-binding
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Palmitate
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

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GO Term
positive regulation of protein phosphorylation
apoptotic process
immune response
signal transduction
protein-containing complex assembly
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
motor neuron apoptotic process
positive regulation of apoptotic signaling pathway

Displaying **all 9** entries
GO Term
plasma membrane
extracellular exosome
death-inducing signaling complex
CD95 death-inducing signaling complex
cytosol
membrane raft
external side of plasma membrane
cell surface
nuclear body

Displaying **all 5** entries
GO Term
signaling receptor activity
kinase binding
identical protein binding
tumor necrosis factor receptor activity
calmodulin binding

Annotation information from UniProt.

Sequence

MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
28	O-linked (GalNAc...) threonine	22171320	G29931IJ G43417UB G57321FI	UniProt GlyGen GlyConnect
38			G57321FI	GlyGen
39			G57321FI	GlyGen
40			G57317CE G57321FI	GlyGen
42			G57321FI	GlyGen
43			G57321FI	GlyGen
46			G43417UB G29068FM G57321FI	GlyGen
118	N-linked (GlcNAc...) asparagine	19159218	G80075MS G85282JO G45395BF G07246CJ G14972EH G43223CG G08918WF G70441OD G87661QW G83646BJ G04657PL G27058EU G83460ZZ G41071NU G07755XJ G86182NS G70619PT G59626AS G08290VR G42124LM G90659AW G62765YT G95177YH G05049YU G23719VF G37995HC	UniProt GlyGen
132				GlyGen
136	N-linked (GlcNAc...) asparagine		G83633GK	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
CASP8 activity is inhibited	Homo sapiens
Dimerization of procaspase-8	Homo sapiens
FasL/ CD95L signaling	Homo sapiens
Ligand-dependent caspase activation	Homo sapiens
RIPK1-mediated regulated necrosis	Homo sapiens
Regulation by c-FLIP	Homo sapiens
TP53 Regulates Transcription of Death Receptors and Ligands	Homo sapiens