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Repository for lectin-assisted multimodality data
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MIRAGE
Tumor necrosis factor receptor superfamily member 6
Summary
- UniProt ID
- P25445
- Gene Symbol
-
- APT1
- FAS
- FAS1
- TNFRSF6
- Gene ID
- 355
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Calmodulin-binding
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| signaling receptor activity |
| calmodulin binding |
| kinase binding |
| identical protein binding |
| tumor necrosis factor receptor activity |
Sequence
MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
Glycosylation Sites
G43417UB
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Homo sapiens |
| Dimerization of procaspase-8 | Homo sapiens |
| FasL/ CD95L signaling | Homo sapiens |
| Ligand-dependent caspase activation | Homo sapiens |
| RIPK1-mediated regulated necrosis | Homo sapiens |
| Regulation by c-FLIP | Homo sapiens |
| TP53 Regulates Transcription of Death Receptors and Ligands | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050523 | adult T-cell leukemia/lymphoma | |
| DOID:0060704 | lymphoproliferative syndrome | |
| DOID:0080797 | nasal type extranodal NK/T-cell lymphoma | |
| DOID:10283 | prostate cancer | |
| DOID:10591 | pre-eclampsia | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11054 | urinary bladder cancer | |
| DOID:13133 | HELLP syndrome | |
| DOID:1485 | cystic fibrosis | |
| DOID:1612 | breast cancer |
