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Clusterin

Summary

UniProt ID

P25473

Gene Symbol

Organism

Canis lupus familiaris (dog)

External Links

PubChem: P25473

Annotation

Keyword

Chaperone
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Membrane
Microsome
Mitochondrion
Nucleus
Phosphoprotein
Reference proteome
Secreted
Signal
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
regulation of cell population proliferation
negative regulation of protein-containing complex assembly
regulation of apoptotic process
positive regulation of apoptotic process
protein stabilization
chaperone-mediated protein folding
positive regulation of receptor-mediated endocytosis
positive regulation of NF-kappaB transcription factor activity
immune complex clearance
response to misfolded protein

Displaying entries **1 - 10** of 11 in total

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2

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GO Term
extracellular space
nucleus
Golgi apparatus
mitochondrion
mitochondrial inner membrane
cytosol
endoplasmic reticulum lumen
spherical high-density lipoprotein particle
chromaffin granule
perinuclear region of cytoplasm

Displaying **all 4** entries
GO Term
protein-folding chaperone binding
misfolded protein binding
ubiquitin protein ligase binding
unfolded protein binding

Annotation information from UniProt.

Sequence

MMKTLLLLVGLLLTWDNGRVLGDQAVSDTELQEMSTEGSKYINKEIKNALKGVKQIKTLIEQTNEERKSLLSNLEEAKKKKEDALNDTKDSETKLKASQGVCNDTMMALWEECKPCLKQTCMKFYARVCRSGSGLVGHQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHALDVMQDSFNRASSIMDELFQDRFFTREPQDTYHYSPFSLFQRRPFFNPKFRIARNIIPFPRFQPLNFHDMFQPFFDMIHQAQQAMDVNLHRIPYHFPIEFPEEDNRTVCKEIRHNSTGCLKMKDQCEKCQEILSVDCSSNNPAQVQLRQELSNSLQIAEKFTKLYDELLQSYQEKMFNTSSLLKQLNEQFSWVSQLANLTQSEDPFYLQVTTVGSQTSDSNVPVGFTKVVVKLFDSDPITVMIPEAVSRNNPKFMETVAEKALQEYRQKHREE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
86	N-linked (GlcNAc...) asparagine	UniProt
103	N-linked (GlcNAc...) asparagine	UniProt
145	N-linked (GlcNAc...) asparagine	UniProt
277	N-linked (GlcNAc...) asparagine	UniProt
287	N-linked (GlcNAc...) asparagine	UniProt
350	N-linked (GlcNAc...) asparagine	UniProt
370	N-linked (GlcNAc...) asparagine	UniProt