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DnaJ homolog subfamily B member 2

Summary

UniProt ID

P25686

Gene Symbol

DNAJB2
HSJ1
HSPF3

Organism

Homo sapiens (human)

External Links

GlyGen: P25686
The O-GlcNAc Database: P25686
RaftProt: P25686
O-GlcNAcAtlas: P25686

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Chaperone
Cytoplasm
Endoplasmic reticulum
Membrane
Methylation
Neurodegeneration
Neuropathy
Nucleus
Phosphoprotein
Prenylation
Reference proteome
Repeat
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

1

2

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GO Term
negative regulation of cell population proliferation
negative regulation of cell growth
negative regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein refolding
negative regulation of inclusion body assembly
negative regulation of protein deubiquitination
regulation of chaperone-mediated protein folding
regulation of protein localization
neuron cellular homeostasis

Displaying **all 9** entries
GO Term
perinuclear region of cytoplasm
cytoplasmic side of endoplasmic reticulum membrane
nucleus
cytoplasm
nuclear membrane
inclusion body
cytosol
proteasome complex
endoplasmic reticulum membrane

Displaying **all 9** entries
GO Term
proteasome binding
protein-folding chaperone binding
ubiquitin-dependent protein binding
Hsp70 protein binding
polyubiquitin modification-dependent protein binding
ubiquitin protein ligase binding
ubiquitin binding
unfolded protein binding
ATPase activator activity

Annotation information from UniProt.

Sequence

MASYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDRYGREGLTGTGTGPSRAEAGSGGPGFTFTFRSPEEVFREFFGSGDPFAELFDDLGPFSELQNRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGRRITTRRIMENGQERVEVEEDGQLKSVTINGVPDDLALGLELSRREQQPSVTSRSGGTQVQQTPASCPLDSDLSEDEDLQLAMAYSLSEMEAAGKKPAGGREAQHRRQGRPKAQHQDPGLGGTQEGARGEATKRSPSPEEKASRCLIL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites