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DnaJ homolog subfamily B member 2

Summary

UniProt ID

P25686

Gene Symbol

DNAJB2
HSJ1
HSPF3

Organism

Homo sapiens (human)

External Links

GlyGen: P25686
The O-GlcNAc Database: P25686
RaftProt: P25686
O-GlcNAcAtlas: P25686

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Chaperone
Cytoplasm
Endoplasmic reticulum
Membrane
Methylation
Neurodegeneration
Neuropathy
Nucleus
Phosphoprotein
Prenylation
Reference proteome
Repeat
Ubl conjugation

Gene Ontology (GO)

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GO Term
negative regulation of protein binding
neuron cellular homeostasis
negative regulation of protein deubiquitination
regulation of chaperone-mediated protein folding
response to unfolded protein
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
ERAD pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
chaperone-mediated protein folding
regulation of protein ubiquitination

Displaying **all 9** entries
GO Term
cytoplasm
proteasome complex
cytoplasmic side of endoplasmic reticulum membrane
endoplasmic reticulum membrane
cytosol
perinuclear region of cytoplasm
nucleus
inclusion body
nuclear membrane

Displaying entries **1 - 10** of 11 in total

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GO Term
protein serine/threonine kinase binding
ubiquitin-dependent protein binding
ATPase activator activity
Hsp70 protein binding
polyubiquitin modification-dependent protein binding
ubiquitin protein ligase binding
ubiquitin binding
protein-folding chaperone binding
proteasome binding
unfolded protein binding

Annotation information from UniProt.

Sequence

MASYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDRYGREGLTGTGTGPSRAEAGSGGPGFTFTFRSPEEVFREFFGSGDPFAELFDDLGPFSELQNRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGRRITTRRIMENGQERVEVEEDGQLKSVTINGVPDDLALGLELSRREQQPSVTSRSGGTQVQQTPASCPLDSDLSEDEDLQLAMAYSLSEMEAAGKKPAGGREAQHRRQGRPKAQHQDPGLGGTQEGARGEATKRSPSPEEKASRCLIL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites