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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Furin-like protease 1, isoforms 1/1-X/2
Summary
- UniProt ID
- P26016
- Gene Symbol
-
- Fur1
- Organism
- Drosophila melanogaster (fruit fly)
External Links
- PubChem
- P26016
Annotation
- Keyword
-
- Alternative splicing
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Reference proteome
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| trans-Golgi network |
| plasma membrane |
| GO Term |
|---|
| serine-type endopeptidase activity |
Sequence
MKNDVVRWSRQPTSNTTNSSSSSRSDSNSTHKHRSKSNKLNARQLGSNAARSCQQRSSVATTLEDEQQTIIECDIGNFNFDCNLFKTSFLTQHKQKRSGKSSSKSKSNRSRPLAKTKAVFLLALQFSAVVFLCNINVGFVAGSVATAASSAGGSSPAAPSSAPSSPPTVAVPPPPPPSSALKVDPNGQSPVLPPYVLDYETGGKAKLTPNNGKFGQSGSSGSNNNHIVGHYTHTWAVHIPNGDNGMADAVAKDHGFVNLGKIFDDHYHFAHHKVSKRSLSPATHHQTRLDDDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGGGLDMNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDPSWSRNGVGRRVSHSFGYGLMDAAEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLTVNHCRSVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEIHNEGRYMGHALLREWSLIFYGTTQSIGPNDPISVPKPSGSEATTPNSSSTTSNLHQAYSPQYPRIPPNNFGSSPSGGSKLPLGKVPPPNKSSYVTNNPLLNSAPPKQGYQQISATYGVILGKANGKSNNNSKEKTNNKGNKSNNGNKGKSGGSSGNRKEQTTQSTIIQTSTSKNKYYRISQQQQQKNNKQDRNGVQTQRPKANSGEKSYDEKSRKVVGEITTNSGNGSIKAAKQVKESTTTSSNSRIPKLFERYEKIQAIFPELEPYENSSPKGKPKQAKQGKQFEVDLFKPTNGGNSRQGNTKKSPSVPPPSQTMATLSILPILPAGGSSFLPDQKILKKQQLLMAAAGVMAPAQVEVEMEEVHATPDYEARKDQRKEVNGPNAQITQWDMIFYGTETPAQPDDVANPSQSNQFNLYGNDMAHNDVEYDSTGQWRNMQQVGEVGMTRDHSNTAACLKWSDRKCLGLSLLFFMIMQVFFLNFKHANDNNNKNKNNIIKCIR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 15 | N-linked (GlcNAc...) asparagine |
|
||
| 18 | N-linked (GlcNAc...) asparagine |
|
||
| 28 | N-linked (GlcNAc...) asparagine |
|
||
| 108 | N-linked (GlcNAc...) asparagine |
|
||
| 333 | N-linked (GlcNAc...) asparagine |
|
||
| 426 | N-linked (GlcNAc...) asparagine |
|
||
| 606 | N-linked (GlcNAc...) asparagine |
|
||
| 727 | N-linked (GlcNAc...) asparagine |
|
||
| 814 | N-linked (GlcNAc...) asparagine |
|
||
| 857 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Drosophila melanogaster |
| Assembly of active LPL and LIPC lipase complexes | Drosophila melanogaster |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | Drosophila melanogaster |
| Signaling by PDGF | Drosophila melanogaster |
| TGF-beta receptor signaling activates SMADs | Drosophila melanogaster |
