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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

P26450

Gene Symbol

Pik3r1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P26450
PubChem: P26450
O-GlcNAcAtlas: P26450

Annotation

Keyword

Acetylation
Direct protein sequencing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
cellular response to insulin stimulus
myeloid leukocyte migration
negative regulation of muscle cell apoptotic process
negative regulation of cell-cell adhesion
positive regulation of tumor necrosis factor production
response to insulin
negative regulation of apoptotic process
positive regulation of myoblast differentiation
negative regulation of osteoclast differentiation
negative regulation of proteolysis

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GO Term
nucleus
cytoplasm
cell-cell junction
membrane
protein-containing complex
perinuclear endoplasmic reticulum membrane
cytosol
cis-Golgi network
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA

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GO Term
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
phosphoprotein binding
phosphotyrosine residue binding
1-phosphatidylinositol-3-kinase activity
insulin receptor binding
insulin-like growth factor receptor binding
platelet-derived growth factor receptor binding
neurotrophin TRKA receptor binding
calmodulin binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
541			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **31 - 40** of 55 in total

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Pathway Name	Organism
RAC2 GTPase cycle	Mus musculus
RAC3 GTPase cycle	Mus musculus
RAF/MAP kinase cascade	Mus musculus
RET signaling	Mus musculus
RHOA GTPase cycle	Mus musculus
RHOB GTPase cycle	Mus musculus
RHOC GTPase cycle	Mus musculus
RHOD GTPase cycle	Mus musculus
RHOF GTPase cycle	Mus musculus
RHOG GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements