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MIRAGE
Phosphatidylinositol 3-kinase regulatory subunit alpha
Summary
- UniProt ID
- P26450
- Gene Symbol
-
- Pik3r1
- Gene ID
- 18708
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Direct protein sequencing
- Phosphoprotein
- Protein transport
- Reference proteome
- Repeat
- SH2 domain
- SH3 domain
- Stress response
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| protein phosphatase binding |
| protein heterodimerization activity |
| 1-phosphatidylinositol-3-kinase activity |
| kinase activator activity |
Sequence
MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| RHOJ GTPase cycle | Mus musculus |
| RHOU GTPase cycle | Mus musculus |
| RHOV GTPase cycle | Mus musculus |
| RND1 GTPase cycle | Mus musculus |
| RND2 GTPase cycle | Mus musculus |
| RND3 GTPase cycle | Mus musculus |
| Regulation of signaling by CBL | Mus musculus |
| Role of LAT2/NTAL/LAB on calcium mobilization | Mus musculus |
| Role of phospholipids in phagocytosis | Mus musculus |
| Signaling by ALK | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111454 | SHORT syndrome | |
| DOID:14179 | X-linked agammaglobulinemia |
