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Activin receptor type-2A
Summary
- UniProt ID
- P27038
- Gene Symbol
-
- Acvr2
- Acvr2a
- Gene ID
- 11480
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003524
- PubChem
- P27038
- Re-Glyco
- P27038
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Magnesium
- Manganese
- Metal-binding
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| receptor complex |
| cell surface |
| inhibin-betaglycan-ActRII complex |
Sequence
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 43 | N-linked (GlcNAc...) asparagine |
|
||
| 66 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Signaling by Activin | Mus musculus |
| Signaling by BMP | Mus musculus |
| TGFBR3 regulates activin signaling | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4258 | Weissenbacher-Zweymuller syndrome |
