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Transforming growth factor beta-2 proprotein

Summary

UniProt ID

P27090

Gene Symbol

Tgfb2

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003526

GlyConnect

2777

GlyGen

P27090

PubChem

P27090

Annotation

Keyword

3D-structure
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Growth factor
Mitogen
Reference proteome
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of **113** in total

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GO Term
blood vessel remodeling
wound healing
regulation of cell population proliferation
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of keratinocyte differentiation
positive regulation of cell cycle
positive regulation of heart contraction
somatic stem cell division

Displaying **all 10** entries
GO Term
extracellular matrix
neuronal cell body
endosome
trans-Golgi network
cell surface
extracellular region
basement membrane
extracellular space
secretory granule
axon

Displaying **all 10** entries
GO Term
amyloid-beta binding
type II transforming growth factor beta receptor binding
cytokine activity
transforming growth factor beta receptor binding
growth factor activity
type III transforming growth factor beta receptor binding
identical protein binding
protein homodimerization activity
protein-containing complex binding
signaling receptor binding

Annotation information from UniProt.

Sequence

MHYCVLSTFLLLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHLPSENAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVQEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYRLESQQSSRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	GlyTouCan ID	Source
72	N-linked (GlcNAc...) asparagine		UniProt GlyGen
140	N-linked (GlcNAc...) asparagine	G80920RR	GlycoProtDB UniProt GlyGen
241	N-linked (GlcNAc...) asparagine	G64527OM	UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Molecules associated with elastic fibres	Mus musculus
Platelet degranulation	Mus musculus
TGF-beta receptor signaling activates SMADs	Mus musculus
TGFBR3 regulates TGF-beta signaling	Mus musculus