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Transforming growth factor beta-2 proprotein

Summary

UniProt ID

P27090

Gene Symbol

Tgfb2

Gene ID

21808

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003526

GlyConnect

Transforming growth factor beta-2

GlyGen

P27090

PubChem

P27090

Re-Glyco

P27090

Annotation

Keyword

3D-structure
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Growth factor
Mitogen
Reference proteome
Signal

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
extracellular region
extracellular space
axon
extracellular matrix
neuronal cell body
endosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of **107** in total

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GO Term
positive regulation of cell division
negative regulation of cartilage development
skeletal system development
blood vessel development
response to hypoxia
neural tube closure
positive regulation of cell population proliferation
negative regulation of cell population proliferation
response to wounding
positive regulation of gene expression

Displaying **all 7** entries
GO Term
signaling receptor binding
amyloid-beta binding
type II transforming growth factor beta receptor binding
transforming growth factor beta receptor binding
growth factor activity
type III transforming growth factor beta receptor binding
protein homodimerization activity

Annotation information from UniProt.

Sequence

MHYCVLSTFLLLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHLPSENAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVQEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYRLESQQSSRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	GlyTouCan ID	Source
72	N-linked (GlcNAc...) asparagine		UniProt GlyGen
140	N-linked (GlcNAc...) asparagine	G80920RR	GlycoProtDB UniProt GlyGen
241	N-linked (GlcNAc...) asparagine	G64527OM	UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Molecules associated with elastic fibres	Mus musculus
Platelet degranulation	Mus musculus
TGF-beta receptor signaling activates SMADs	Mus musculus
TGFBR3 regulates TGF-beta signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements