N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase

Summary
UniProt ID
P27742
Gene Symbol
  • acvA
Organism
Aspergillus nidulans FGSC A4
Annotation
Keyword
  • ATP-binding
  • Antibiotic biosynthesis
  • Cytoplasm
  • Direct protein sequencing
  • Glycoprotein
  • Ligase
  • Membrane
  • Multifunctional enzyme
  • Phosphopantetheine
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Vacuole
Gene Ontology (GO)
Sequence
MSPPGLLSEDGPGYSGGYADPTVPKVNWKQSNGKSAGGNGDVDAGNGNIDPSKSGVGVQVCFAGGLEGWKAGISKITERCDLSSIATNSTKYQLAVTGFSDGPDDYNEYSVPFPSEVLVAMEEMCLARDISMRSVIQFAVHYVLKGFGGGSHTVAASIDVGDDPNNIATSYTITPSIVCHESRQGQTVMQEIQSMEKLNQLRKQEMHPGEAGLSLIRMGLFDILVIFADANKCEGLIAGLPLAVMVCEGGGRLQVRIHFSGSLFRQKTLVDIAEALNVLFAKAASGGATPVRDLELLSAEQKQQLEEWNKTDGEYPECKRLNHLIEEATQLHEDKVAIVYKRRQLTYGELNAQANCFAHYLRSIGILPEQLVALFLEKSENLIVTILGIWKSGAAYVPIDPTYPDERVRFVLEDTQAKVIIASNHLAERLQSEVISDRELSIIRLEHCLSAIDQQPSTFPRANLRDPSLTSKQLAYVTYTSGTTGFPKGILKQHTNVVNSITDLSARYGVTGDHHEAILLFSAYVFEPFVRQMLMALVNGHLLAMVDDAEKYDAEKLIPFIREHKITYLNGTASVLQEYDFSSCPSLKRLILVGENLTESRYLALRRHFKNCILNEYGFTESAFVTALNVFEPGSARNNTSLGRPVRNVKCYILNKSLKRVPIGATGELHIGGLGISKGYLNRPDLTPQRFIPNPFQTDHEKELGLNQLMYKTGDLARWLPNGEIEYLGRADFQIKLRGIRIEPGEIESTLAGYPGVRTSLVVSKRLRHGEKETTNEHLVGYYVGDNTSVSETALLQFLELKLPRYMIPTRLVRVSQIPVTVNGKADLRALPSVDLIQPKVSSCELTDEVEIALGKIWADVLGAHHLSISRKDNFFRLGGHSITCIQLIARIRQQLGVIISIEDVFSSRTLERMAELLRSKESNGTPDERARPQLKTVAGEVANANVYLANSLQQGFVYQFLKNMGRSEAYVMQSVLRYDVNINPDLFKKAWKQVQHMLPTLRLRFQWGQDVLQVIDEDQPLNWWFLHLADDSALPEEQKLLELQRRDLAEPYDLAAGSLFRIYLIEHSSTRFSCLFSCHHAILDGWSLPLLFRKTHGTYLHLLHGHSLRTLEDPYRQSQQYLQDHREDHLRYWAGIVNQIEERCDMNALLNERSRYKIQLADYDKVEDQQQLTLTVPDASWLSKLRQTCSAQGITLHSILQFVWHAVLHAYGGGTHTVTGTTISGRNLPVSGIERSVGLYINTLPLVINQLAYKNKTVLEAIRDVQAIVNGMNSRGNVELGRLQKNELKHGLFDSLFVLENYPILDKSEEMRQKSELKYTIEGNIEKLDYPLAVIAREVDLTGGFTFTICYARELFDEIVISELLQMVRDTLLQVAKHLDDPVRSLEYLSSAQMAQLDAWNATDAEFPDTTLHAMFEKEAAQKPDKVAVVYEQRSLTYRQLNERANRMAHQLKSDISPKPNSIIALVVDKSEHMIATILAVWKTGGAYVPIDPEYPDDRIRYILEDTSAIAVISDACYLSRIQELAGESVRLYRSDISTQTDGNWSVSNPAPSSTSTDLAYIIYTSGTTGKPKGVMVEHHGVVNLQISLSKTFGLRDTDDEVILSFSNYVFDHFVEQMTDAILNGQTLVMLNDAMRSDKERLYQYIETNRVTYLSGTPSVISMYEFSRFKDHLRRVDCVGEAFSQPVFDQIRDTFQGLIINGYGPTEISITTHKRLYPFPERRTDKSIGQQIGNSTSYVLNADMKRVPIGAVGELYLGGEGVARGYHNRPEVTAERFLRNPFQTDSERQNGRNSRLYRTGDLVRWIPGSNGEIEYLGRNDFQVKIRGLRIELGEIEAVMSSHPDIKQSVVIAKSGKEGDQKFLVGYFVASSPLSPGAIRRFMQSRLPGYMIPSSFIPISSLPVTPSGKLDTKALPTAEEKGAMNVLAPRNEIESILCGIWAGLLDISAQTIGSDSDFFTLGGDSLKSTKLSFKIHEVFGRTISVSALFRHRTIESLAHLIMNNVGDIQEITPVDYDNRRKIAVSPAQERLLFIHELEGGGNAYNIDAAFELPPYIDQSRVEEALYTILSRHEALRTFLLRDQATGTFYQKILTTDEAKCMLIIEKSAVSTIDQIDSIVGRLSQHIFRLDSELPWLAHIVTHKTGNLYLTLSFHHTCFDAWSLKIFERELRVFCASNEKGGNMPILPMPQVQYKEYAEHHRRRLGKNQIQKLSDFWLQRLDGLEPLQLLPDYPRPAQFNYDGGDLSVILDGVVLETLRGIAKDHGVTLYAVLLAVYCLMLSTYTHQVDIAVGVPISHRTHPLFQSIVGFFVNMVVVRVDVKDFAVHDLIRRVMKALVDAQLHQDMPFQDVTKLLRVDNDASRHPLVQTVFNFESDMDKEFETTPSIQDTATIAPYQSVQRIKSVAKFDLNATATESGSALKINFNYATSLFRKETIQGFLETYRHLLLQLSYLGSQGLKEDTKLLLVRPEEMSGPHLPLAGLSNGAETLEAISLSRAFEFEAFRVPDRAAVVQGDKSLSYTELNKRANQLARYIQSVAHLRPDDKVLLILDKSIDMIICILAIWKTGSAYVPLDPSYPKERVQCISEVVQAKILITESRYASAWGSQTSTILAIDSPKVSNMVNNQATHNLPNIAGIKNLAYIIFTSGTSGKPKGVLVEQGGVLHLRDALRKRYFGIECNEYHAVLFLSNYVFDFSIEQLVLSIMSGHKLIIPEGEFVADDEFYITANGQRLSYLSGTPSLLQQIDLARLNHLQVVTAAGEQLHAAQFNKLRSGFRGPIYNAYGITETTVYNIVSEFSAQSQFENALRELLPGTRAYLLNHATQPVPMNAVGELYLAGDCVARGYLNQPVLTGDRFIQNPFQTEQDIASGSYPRLYRTGDLFRCRLDRQHQPYLEYLGRADLQVKIRGYRIEPSEVQNVLASCPGVRECAVVAKYENTDAYSRIAKFLVGYYTPDTETVSDSSILAHMKSKLPAYMVPKYLCRLEGGLPVTINGKLDVRKLPDIGNPQHQISYNPPRDVLEADLCRLWASALGTERCGIDDDLFRLGGDSITALHLAAQIHHQIGRKVTVRDIFDHPTIRGIHDNVMVKLVPHNVPQFQAEQQTVLGDAPLLPIQTWFLSKSLQHPSHWNHTFYLRTPELDVTTLSTAVAELQLYHDAFRMRLRQIDGRTVQCFADDISPVQLRVLNVKDVDGSAAIDQQLQKYQSDFDLEKGPICAAAYLHGYEDRSARVWFSVHHIIIDIVSWQILARDLQILYEGGTLGRKSSSVRQWAEALQSYQGSASERAYWEGLLAQTAANISALPPVTGTRTRLARTWSDDRTVILLNEASNQNASIQDLLLAAVGLALQQVTPGSPSMITLEGHGREEIVDPTLDLSRTLGWFTSMYPFEIPPLNVETLSQGIASLRECLRQVPARGIGFGSLYGYCKHQMPQVTFNYLGQLTSKQSITDQWALAVGDGEMQYGLTTSPADRDQSSFAVDITASCVNGALSVEMNSAWSLEKSMRFISRIEEVLNMILSGTLAQQATPVLTPQVFNEEMYTPYFEFSKTPRRGPILFLLPPGEGGAESYFNNIVKHLPTTNMVVFNNYYLHSKSLNTFEKLAEMYLGHIRQIQPDGPYHFIGWSFGGTIAMEISRQLVGLGSTIGLLGIIDTYFNVPGATRAIGLGDTEVLDPIHHISQPEPADFQCLPASTDYIILFKATRVNDKFQSENQRRLYEYYDKTLLNDLDWLLPGASNIHLVRLEEDTHFSWATNPRQIAHVCSTIEKFLARY
Glycosylation Sites
Displaying entries 11 - 16 of 16 in total
Position Description PubMed ID GlyTouCan ID Source
1545 N-linked (GlcNAc...) asparagine
1735 N-linked (GlcNAc...) asparagine
2410 N-linked (GlcNAc...) asparagine
3130 N-linked (GlcNAc...) asparagine
3298 N-linked (GlcNAc...) asparagine
3332 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024