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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Calreticulin
Summary
- UniProt ID
- P27797
- Gene Symbol
-
- CALR
- CRTC
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Calcium
- Chaperone
- Cytoplasm
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Extracellular matrix
- Glycoprotein
- Hydroxylation
- Lectin
- Lysosome
- Metal-binding
- Reference proteome
- Repeat
- Sarcoplasmic reticulum
- Signal
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| acrosomal vesicle |
| extracellular region |
| extracellular space |
| nucleus |
| nuclear envelope |
| cytoplasm |
| ribosome |
| membrane |
| collagen-containing extracellular matrix |
| extracellular exosome |
| GO Term |
|---|
| peptide binding |
| hormone binding |
| carbohydrate binding |
| nuclear androgen receptor binding |
| protein-folding chaperone binding |
| ubiquitin protein ligase binding |
| protein folding chaperone |
| unfolded protein binding |
Sequence
MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 325 |
|
|||
| 344 | N-linked (GlcNAc...) asparagine |
|
||
| 346 |
|
|||
| 350 |
|
G49108TO
G33416PL
G76295SF
G51653BI
G83460ZZ
G92406TI
G46503DX
G25079LO
G70101JE
G80920RR
G77547TA
G59924QI
G83633GK
G62765YT
G64527OM
G95177YH
G05049YU
G18647XP
G05724UK
G31852PQ
G90575OW
G72787SB
G23719VF
G49874UX
G22572EH
G39188ZX
G41247ZX
G23453IV
G57776ZU
G36379GD
G94854LT
G02815KT
G06110VR
G57317CE
G60145BJ
G92050GC
G74724QE
G92275SC
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ATF6 (ATF6-alpha) activates chaperone genes | Homo sapiens |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | Homo sapiens |
| Assembly of Viral Components at the Budding Site | Homo sapiens |
| Calnexin/calreticulin cycle | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| Scavenging by Class A Receptors | Homo sapiens |
| Scavenging by Class F Receptors | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060781 | congenital secretory sodium diarrhea 3 | |
| DOID:0060891 | Parkinson's disease 19A | |
| DOID:0060895 | Parkinson's disease 4 | |
| DOID:0060896 | Parkinson's disease 23 | |
| DOID:0070094 | oculocutaneous albinism type IA | |
| DOID:0070113 | Niemann-Pick disease type C1 | |
| DOID:0080070 | mucolipidosis II alpha/beta | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080187 | chronic neutrophilic leukemia |
