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Interleukin-1 receptor type 2

Summary

UniProt ID

P27930

Gene Symbol

IL1R2
IL1RB

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0015604

GlyConnect

1949

GlyGen

P27930

PubChem

P27930

RaftProt

P27930

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
immune response
negative regulation of protein processing
protein processing
negative regulation of cytokine production involved in inflammatory response
negative regulation of interleukin-1 alpha production
negative regulation of interleukin-1-mediated signaling pathway

Displaying **all 3** entries
GO Term
extracellular region
cytoplasm
plasma membrane

Displaying **all 3** entries
GO Term
interleukin-1 receptor activity
interleukin-1 binding
interleukin-1, type II, blocking receptor activity

Annotation information from UniProt.

Sequence

MLRLYVLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
66	N-linked (GlcNAc...) asparagine		G38663NM G33791AF G11629QQ G48414YA	GlycoProtDB UniProt GlyGen GlyConnect
72	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
112	N-linked (GlcNAc...) asparagine	20802483		UniProt GlyGen
219	N-linked (GlcNAc...) asparagine	20802483	G62461SM G55412XP G33791AF G56784JY G22310AV G37509XX G70223PD	GlycoProtDB UniProt GlyGen GlyConnect
277	N-linked (GlcNAc...) asparagine			UniProt GlyGen