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MIRAGE
Interleukin-1 receptor type 2

Summary
UniProt ID
P27930
Gene Symbol
  • IL1R2
  • IL1RB
Gene ID
7850
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0015604
GlyConnect
GlyGen
P27930
PubChem
P27930
RaftProt
P27930
Re-Glyco
P27930
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Receptor
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 4 entries
GO Term
cell surface
extracellular region
cytoplasm
plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MLRLYVLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
66 N-linked (GlcNAc...) asparagine
72 N-linked (GlcNAc...) asparagine
112 N-linked (GlcNAc...) asparagine
219 N-linked (GlcNAc...) asparagine
277 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Interleukin-1 signaling Homo sapiens
Interleukin-10 signaling Homo sapiens
Disease
Displaying all 4 entries
DO ID Disease Name Source
DOID:0050686 organ system cancer
DOID:1324 lung cancer
DOID:1474 aggressive periodontitis
DOID:5041 esophageal cancer
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025