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Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

Summary

UniProt ID

P28241

Gene Symbol

IDH2
O3326
YOR136W
YOR3326W

Gene ID

854303

Organism

Saccharomyces cerevisiae S288C

External Links

GlyGen: P28241
PubChem: P28241
O-GlcNAcAtlas: P28241
Re-Glyco: P28241

Annotation

Keyword

3D-structure
Allosteric enzyme
Direct protein sequencing
Magnesium
Manganese
Metal-binding
Mitochondrion
NAD
Oxidoreductase
Phosphoprotein
RNA-binding
Reference proteome
Transit peptide
Tricarboxylic acid cycle

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
isocitrate dehydrogenase complex (NAD+)
mitochondrion
mitochondrial matrix

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 3** entries
GO Term
glutamate biosynthetic process
tricarboxylic acid cycle
isocitrate metabolic process

Displaying **all 4** entries
GO Term
magnesium ion binding
RNA binding
isocitrate dehydrogenase (NAD+) activity
NAD binding

Annotation information from UniProt.

Sequence

MLRNTFFRNTSRRFLATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites