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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mitogen-activated protein kinase 1
Summary
- UniProt ID
- P28482
- Gene Symbol
-
- MAPK1
- ERK2
- PRKM1
- PRKM2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P28482
- PubChem
- P28482
- The Human Metabolome Database
- HMDBP01190
- The O-GlcNAc Database
- P28482
- RaftProt
- P28482
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cell cycle
- Cell junction
- Cytoskeleton
- DNA-binding
- Direct protein sequencing
- Disease variant
- Host-virus interaction
- Membrane
- Nucleus
- Phosphoprotein
- Reference proteome
- Repressor
- Serine/threonine-protein kinase
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| extracellular region |
| Golgi apparatus |
| cytoskeleton |
| plasma membrane |
| synapse |
| pseudopodium |
| mitotic spindle |
| mitochondrion |
| cytosol |
Sequence
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of the AP-1 family of transcription factors | Homo sapiens |
| Advanced glycosylation endproduct receptor signaling | Homo sapiens |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | Homo sapiens |
| ERK/MAPK targets | Homo sapiens |
| ERKs are inactivated | Homo sapiens |
| ESR-mediated signaling | Homo sapiens |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | Homo sapiens |
| Estrogen-stimulated signaling through PRKCZ | Homo sapiens |
| FCERI mediated MAPK activation | Homo sapiens |
| FCGR3A-mediated phagocytosis | Homo sapiens |
Human Protein Atlas