GlyCosmos Portal

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Decorin

Summary

UniProt ID

P28654

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003535

GlyConnect

2250

GlyGen

P28654

PubChem

P28654

Annotation

Keyword

Disulfide bond
Extracellular matrix
Leucine-rich repeat
Proteoglycan
Reference proteome
Repeat
Signal

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
positive regulation of transcription by RNA polymerase II
negative regulation of angiogenesis
positive regulation of macroautophagy
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
negative regulation of vascular endothelial growth factor signaling pathway
negative regulation of endothelial cell migration
positive regulation of mitochondrial depolarization
positive regulation of mitochondrial fission

Displaying **all 3** entries
GO Term
extracellular space
collagen-containing extracellular matrix
collagen type VI trimer

Displaying **all 3** entries
GO Term
extracellular matrix binding
collagen binding
glycosaminoglycan binding

Annotation information from UniProt.

Sequence

MKATLIFFLLAQVSWAGPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWDFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNQLKELPEKMPRTLQELRVHENEITKLRKSDFNGLNNVLVIELGGNPLKNSGIENGAFQGLKSLSYIRISDTNITAIPQGLPTSLTEVHLDGNKITKVDAPSLKGLINLSKLGLSFNSITVMENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYIQVVYLHNNNISAVGQNDFCRAGHPSRKASYSAVSLYGNPVRYWEIFPNTFRCVYVRSAIQLGNYK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	GlyTouCan ID	Source
34	O-linked (Xyl...) (glycosaminoglycan) serine		UniProt GlyGen
206	N-linked (GlcNAc...) asparagine	G02815KT G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
241	N-linked (GlcNAc...) asparagine	G92275SC	UniProt GlyGen
257	N-linked (GlcNAc...) asparagine	G42124LM	GlycoProtDB UniProt GlyGen
298	N-linked (GlcNAc...) asparagine	G83633GK	GlycoProtDB UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
A tetrasaccharide linker sequence is required for GAG synthesis	Mus musculus
CS/DS degradation	Mus musculus
Chondroitin sulfate biosynthesis	Mus musculus
Degradation of the extracellular matrix	Mus musculus
Dermatan sulfate biosynthesis	Mus musculus
ECM proteoglycans	Mus musculus