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Progranulin

Summary

UniProt ID

P28798

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003538
GlyGen: P28798
The O-GlcNAc Database: P28798
RaftProt: P28798
O-GlcNAcAtlas: P28798

Annotation

Keyword

Cytokine
Direct protein sequencing
Disulfide bond
Glycoprotein
Lysosome
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 41 in total

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GO Term
lysosomal transport
positive regulation of angiogenesis
negative regulation of innate immune response
epithelial cell proliferation
positive regulation of epithelial cell proliferation
regulation of inflammatory response
negative regulation of inflammatory response
negative regulation of respiratory burst involved in inflammatory response
positive regulation of inflammatory response to wounding
positive regulation of defense response to bacterium

Displaying entries **1 - 10** of 16 in total

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GO Term
late endosome
endoplasmic reticulum
Golgi apparatus
trans-Golgi network
extracellular region
extracellular space
mitochondrion
lysosome
plasma membrane
membrane

Displaying **all 2** entries
GO Term
cytokine activity
protein-folding chaperone binding

Annotation information from UniProt.

Sequence

MWVLMSWLAFAAGLVAGTQCPDGQFCPVACCLDQGGANYSCCNPLLDTWPRITSHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDPVPRPLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine		UniProt GlyGen
263	N-linked (GlcNAc...) asparagine	G80920RR	GlycoProtDB UniProt GlyGen
373	N-linked (GlcNAc...) asparagine	G07755XJ	GlycoProtDB UniProt GlyGen
374			GlycoProtDB
526	N-linked (GlcNAc...) asparagine	G80920RR	GlycoProtDB UniProt GlyGen
528		G49108TO	GlyGen The O-GlcNAc Database